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Screening of biological activities of ligustrum lucidum berries: a comparative approach

2018Journal article Open access
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dc.contributor.authorDelgado, Teresa
dc.contributor.authorPaula, Vanessa B.
dc.contributor.authorCampos, Maria G.
dc.contributor.authorFarinha, Nelson
dc.contributor.authorCaeiro, André
dc.contributor.authorEstevinho, Leticia M.
dc.contributor.authorAnjos, Ofélia
dc.date.accessioned2019-07-16T10:20:27Z
dc.date.available2019-07-16T10:20:27Z
dc.date.issued2018
dc.description.abstractLigustrum lucidum Aiton including its berries have been used in Chinese Traditional Medicine for around 2000 years. Scientific studies developed on the last decades provided evidence on some biological properties of these products, mostly from particular geographic origins. In the present study, L. lucidium berries harvested in two regions of Portugal were considered. Extracts obtained with 100% ethanol, with 50% ethanol/water (v/v) and in boiled water were prepared and several parameters were assessed: antioxidant activity (using two methodologies), antimicrobial activity and phenolic profile. Results suggest that the different biological activities varied according to the region where samples were collected but also with the extraction methodology. Superior antioxidant potential was observed in water extracts, according to both assays, while for the remaining activities the ethanol 50% extracts had the highest activity. In these regions, the L. lucidum berries showed promising biological activities and may be interesting sources of compounds for the development of new drugs for diseases where oxidant reactive species and enzymatic disruption are believed to play a role as well as adjuvants for current antibiotic therapy.pt_PT
dc.description.sponsorshipThe author Anjos O. wishes to thank to Centro de Estudos Florestais that is a research unit funded by FCT (UID/AGR/UI00239/2013). The author Campos M.G. wishes to thank to the “Strategic Project RG-Centre-177-3717 from Science and Technology Foundation”, UID/QUI/00313/2013 and POCI-01-0145-FEDER-007630 (Portugal). The author Estevinho M.L. wishes to thank to the strategic programmer UID/BIA/04050/2013 (POCI-01-0145-FEDER- 007569) funded by national funds through the Fundação para a Ciência e a Tecnologia (FCT), Portugal and by the European Regional Development Fund (ERDF) through the COMPETE2020- Programa Operacional Competitividade e Internacionalização (POCI). The authors would like to express their gratitude to Isabele Salavessa (IPCB Languages Centre) for the English revision.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDelgado, Teresa; Paula, Vanessa B.; Campos, Maria Graça; Farinha, Nelson; Caeiro, André; Estevinho, Leticia M.; Anjos, Ofélia (2018). Screening of biological activities of ligustrum lucidum berries: a comparative approach. Natural Product Communications. ISSN 1934-578X. 13:12, p. 1685-1690pt_PT
dc.identifier.issn1934-578X
dc.identifier.urihttp://hdl.handle.net/10198/19437
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationUID/AGR/U100239/2013pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectLigustrum lucidum Aiton berriespt_PT
dc.subjectAntioxidant activitypt_PT
dc.subjectAntimicrobial activitypt_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectNatural compoundspt_PT
dc.subjectBiological propertiespt_PT
dc.titleScreening of biological activities of ligustrum lucidum berries: a comparative approachpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F00313%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FBIA%2F04050%2F2013/PT
oaire.fundingStream5876
oaire.fundingStream5876
person.familyNamePaula
person.familyNameEstevinho
person.givenNameVanessa B.
person.givenNameLetícia M.
person.identifier.ciencia-id5F16-A866-562D
person.identifier.ciencia-idBA14-09D6-A406
person.identifier.orcid0000-0001-7281-8598
person.identifier.orcid0000-0002-9249-1948
person.identifier.scopus-author-id6506577664
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isProjectOfPublication273743b2-1344-4cc0-964e-39ea6dc23de5
relation.isProjectOfPublication78617fc7-4718-447c-a308-5b39e4818848
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