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In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi

dc.contributor.authorBoughanmi, Mohamed Belhassan
dc.contributor.authorBranco, Iuliia
dc.contributor.authorChoupina, Altino
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2021-12-02T16:31:46Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2021-12-02T16:31:46Z
dc.date.issued2021
dc.description.abstractPhytophthora cinnamomi is classified as one of the most devastating plant pathogens in the world. It has a destructive effect on more than 5000 horticultural and forestry species in the world, and especially on Castanea sativa. The genus Phytophthora belongs to the Class Oomycetes, a group of fungus like organisms which provoke plant diseases via motile zoospores. Control of this organism is considered very challenging because of the limited range of effective chemical inhibitors. The development of sustainable control measures for the future management of P. cinnamomi requires in-depth knowledge of the cellular and molecular bases of development and metabolism. The aim of this review was to identify molecular factors associated with the metabolism of P. cinnamomi by studying the genes implicated in fundamental metabolism using tools of bioinformatics. Also, some genes involved in pathogenicity will be cited and characterized, such as genes coding for transglycosylases. Genomic sequences of P. cinnamomi were analyzed using an open reading frame (ORF) finder. The identified ORFs products (proteins) were compared to sequences already described and with known functions present in databases such as NCBI and fungi database. In this way, homologous proteins were found, with the respective specific domains, to proteins involved in the metabolism and pathogenicity of Phytophthora ssp.en_EN
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2019).
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationBoughanmi, Mohamed Belhassan; Branco, Iuliia; Choupina, Altino (2021) - In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi. Molecular Biology Reports. ISSN 0301-4851. p. 1-11en_EN
dc.identifier.doi10.1007/s11033-021-06901-0en_EN
dc.identifier.issn0301-4851
dc.identifier.urihttp://hdl.handle.net/10198/24436
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationMountain Research Centre
dc.subjectCastanea sativaen_EN
dc.subjectOomycetesen_EN
dc.subjectOpen reading frameen_EN
dc.subjectPhytophthora cinnamomien_EN
dc.subjectZoosporesen_EN
dc.titleIn silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomien_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMountain Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FAGR%2F00690%2F2019/PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameChoupina
person.givenNameAltino
person.identifier587972
person.identifier.ciencia-id1A14-77FC-9656
person.identifier.orcid0000-0002-3956-9398
person.identifier.ridL-5382-2014
person.identifier.scopus-author-id14051602500
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublication314b895b-a5e2-4a92-9bc6-dd708c819be4
relation.isAuthorOfPublication.latestForDiscovery314b895b-a5e2-4a92-9bc6-dd708c819be4
relation.isProjectOfPublicationd6683ba1-d253-48e4-968e-35106ce7b750
relation.isProjectOfPublication.latestForDiscoveryd6683ba1-d253-48e4-968e-35106ce7b750

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