Repository logo
 
Publication

Mushrooms as a source of compounds that induce programmed cell death in tumour cells

2016Book part Restricted access
Simple item page
dc.contributor.authorReis, Filipa S.
dc.contributor.authorMorales, Patricia
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorVasconcelos, M. Helena
dc.date.accessioned2018-02-20T12:36:43Z
dc.date.available2018-02-20T12:36:43Z
dc.date.issued2016
dc.description.abstractOne of the hallmarks of cancer is the ability of tumour cells to resist cell death. Consequently, therapies based on the induction of programmed cell death (PCD) constitute an area of scientific interest. Mushrooms are a demonstrated source of extracts and compounds with antitumour properties. One of such properties is the capacity to induce PCD. This chapter reviews the existing evidence of mushroom extracts inducing apoptosis or autophagy in human tumour cell lines and focuses on the identified compounds that are responsible for those cellular activities including the known pathways involved. This chapter is intended to identify the most bioactive classes of compounds and the cell lines in which they exert their activity. This information aims to present the basis for future works, in order to obtain or create new therapies for the treatment of cancer, including pharmaceutical and/or nutraceutical products.pt_PT
dc.description.sponsorshipD. Sousa and R.T.Lima for critical comments to the Figures. QREN for the grant of F.S.Reis (NORTE-07-0124-FEDER-000023). IPATIMUP is an Associate Laboratory of the Portuguese Ministry of Science, Technology and Higher Education and is partially supported by Fundação para a Ciencia e a Tecnologia (FCT).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationReis, Filipa S.; Morales, Patricia; Ferreira, Isabel C.F.R.; Vasconcelos, Maria Helena (2016). Mushrooms as a source of compounds that induce programmed cell death in tumour cells. In . (Ed.) J.N. Govil, Manohar Pathak Phytotherapeutics II, Chapter 5. p. 85-119. ISBN 978-1626990807pt_PT
dc.identifier.issn978-1626990807
dc.identifier.urihttp://hdl.handle.net/10198/15834
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherStudium Presspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectMushroom extractspt_PT
dc.subjectBioactive compoundspt_PT
dc.subjectProgrammed cell deathpt_PT
dc.subjectApoptosispt_PT
dc.subjectAutophagypt_PT
dc.titleMushrooms as a source of compounds that induce programmed cell death in tumour cellspt_PT
dc.typebook part
dspace.entity.typePublication
oaire.citation.titlePhytotherapeutics-II in the series on Recent Progress in Medicinal Plantspt_PT
person.familyNameReis
person.familyNameFerreira
person.givenNameFilipa S.
person.givenNameIsabel C.F.R.
person.identifier144781
person.identifier.ciencia-id391F-AFE1-64C7
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9159-0530
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridI-2093-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id36982144400
person.identifier.scopus-author-id36868826600
rcaap.rightsrestrictedAccesspt_PT
rcaap.typebookPartpt_PT
relation.isAuthorOfPublicationb8d384ae-2134-4735-93a6-0d2febbf9220
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
CapiCC81tulo4.pdf
Size:
898.31 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Capítulos de Livros