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Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal

2015Journal article Open access
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dc.contributor.authorMiguel, Maria da Graça
dc.contributor.authorGago, Custódia
dc.contributor.authorAntunes, Maria Dulce
dc.contributor.authorMegías, Cristina
dc.contributor.authorCortés-Giraldo, Isabel
dc.contributor.authorVioque, Javier
dc.contributor.authorLima, Ana Sofia
dc.contributor.authorFigueiredo, Ana Cristina
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2018-03-01T16:05:05Z
dc.date.accessioned2018-03-05T09:18:57Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2018-03-01T16:05:05Z
dc.date.available2018-03-05T09:18:57Z
dc.date.issued2015
dc.description.abstractThe antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS < sup > ·+ < /sup > and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.en_EN
dc.description.sponsorshipThis study was partially funded by Fundac¸˜ao para a Ciˆencia e Tecnologia (FCT), under Pest-OE/EQB/LA0023/2011 and UID/AMB/50017/2013.
dc.description.sponsorshipThis study was partially funded by Fundac¸˜ao para a Ciˆencia e Tecnologia (FCT), under Pest-OE/EQB/LA0023/2011 and UID/AMB/50017/2013.
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationMiguel, Maria Graça; Gago, Custódia; Antunes, Maria Dulce; Megías, Cristina; Cortés-Giraldo, Isabel; Vioque, Javier; Lima, A. Sofia; Figueiredo, A. Cristina (2015). Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal. Evidence-based Complementary and Alternative Medicine. ISSN 1741-427X. 2015, p.en_EN
dc.identifier.doi10.1155/2015/851721en_EN
dc.identifier.isbn1741-427X
dc.identifier.urihttp://hdl.handle.net/10198/16135
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationStrategic Project - LA 23 - 2011-2012
dc.titleAntioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugalen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - LA 23 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0023%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAMB%2F50017%2F2013/PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream5876
person.familyNameLima
person.givenNameAna Sofia
person.identifier.ciencia-idBA18-196F-F34C
person.identifier.orcid0000-0002-4740-1552
person.identifier.ridA-8917-2016
person.identifier.scopus-author-id35074306100
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublicationbd347b7c-34e3-42ca-a7cc-f044586a9fe9
relation.isAuthorOfPublication.latestForDiscoverybd347b7c-34e3-42ca-a7cc-f044586a9fe9
relation.isProjectOfPublication3c8ac4fd-3236-48d7-9b68-5232118916e0
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