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Pieris brassicae inhibits xanthine oxidase.

dc.contributor.authorSousa, Carla
dc.contributor.authorPereira, David M.
dc.contributor.authorValentão, Patrícia
dc.contributor.authorFerreres, Frederico
dc.contributor.authorPereira, J.A.
dc.contributor.authorSeabra, Rosa M.
dc.contributor.authorAndrade, Paula B.
dc.date.accessioned2011-01-13T15:42:43Z
dc.date.available2011-01-13T15:42:43Z
dc.date.issued2009
dc.description.abstractThe antioxidant potential of an aqueous extract obtained from Pieris brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout.por
dc.description.sponsorshipFCTpor
dc.identifier.citationSousa, C.; Pereira, D.M.; Valentão, P.; Ferreres, F.; Pereira, J.A.; Seabra, R.M.; Andrade, P.B. (2009). Pieris brassicae inhibits xanthine oxidase. Journal of Agricultural and Food Chemistry. ISSN 0021-8561. 57:6, p. 2288-2294por
dc.identifier.doi10.1021/jf803831v
dc.identifier.eissn1520-5118
dc.identifier.issn0021-8561
dc.identifier.urihttp://hdl.handle.net/10198/3102
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherACSpor
dc.relationPieris brassicae as laboratory of synthesis of new compounds with biological potential, starting from Brassica oleracea var. costata, Brassica oleracea var. acephala and Brassica rapa var. rapa.
dc.subjectPieris brassicaepor
dc.subjectBrassica oleracea var. costatapor
dc.subjectPhenolic compoundspor
dc.subjectAntioxidant activitypor
dc.titlePieris brassicae inhibits xanthine oxidase.por
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitlePieris brassicae as laboratory of synthesis of new compounds with biological potential, starting from Brassica oleracea var. costata, Brassica oleracea var. acephala and Brassica rapa var. rapa.
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FAGR-AAM%2F64150%2F2006/PT
oaire.citation.endPage2294por
oaire.citation.issue57por
oaire.citation.startPage2288por
oaire.citation.titleJournal of Agricultural and Food Chemistrypor
oaire.fundingStream5876-PPCDTI
person.familyNamePereira
person.givenNameJosé Alberto
person.identifier.ciencia-id611F-80B2-A7C1
person.identifier.orcid0000-0002-2260-0600
person.identifier.ridL-6798-2014
person.identifier.scopus-author-id57204366348
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication7932162e-a2da-4913-b00d-17babbe51857
relation.isAuthorOfPublication.latestForDiscovery7932162e-a2da-4913-b00d-17babbe51857
relation.isProjectOfPublicationf81a81fb-2f99-45fe-bab7-2267d47bf7f3
relation.isProjectOfPublication.latestForDiscoveryf81a81fb-2f99-45fe-bab7-2267d47bf7f3

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