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Inflammation: what's there and what's new?

2023Journal article Open access
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dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorHaddad, Hala
dc.contributor.authorRibeiro, Lucia M.
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorCarocho, Márcio
dc.contributor.authorBarros, Lillian
dc.date.accessioned2020-06-17T10:12:13Z
dc.date.available2020-06-17T10:12:13Z
dc.date.issued2023
dc.description.abstractSince the dawn of man, inflammation has been known to humanity, as it is marked by pain. Inflammation processes are related to serious chronic diseases with irreversible damage to the organism, being crucial for the development of anti-inflammatory agents. Among the existing anti-inflammatory drugs, non-steroidal and glucocorticoids are commonly used; however, these compounds have been described as responsible for the increased risk of upper gastrointestinal complications and many other side effects. Therefore, it is not shocking that ethnobotany leads most modern studies on the discovery of anti-inflammatory agents obtained from natural matrices. Extracts from plants and isolated substances have demonstrated anti-inflammatory effects in a set of in vitro and in vivo anti-inflammatory models. This review describes inflammation processes with an emphasis on the most common related diseases, while also describing the most promising natural anti-inflammatory agents, by reporting on their obtention processes, mechanisms of action, and applications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCalhelha, Ricardo C.; Haddad, Hala; Ribeiro, Lucia M.; Heleno, Sandrina A.; Carocho, Márcio; Barros, Lillian (2023). Inflammation: what's there and what's new?. Applied Sciences. eISSN 2076-3417. 13:4, p. 1-26pt_PT
dc.identifier.doi10.3390/app13042312
dc.identifier.eissn2076-3417
dc.identifier.urihttp://hdl.handle.net/10198/22089
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectInflammation
dc.subjectSynthetic anti-inflammatory agents
dc.subjectNatural anti-inflammatory agents
dc.subjectMechanisms of action
dc.subjectIn vitro and in vivo anti-inflammatory assays
dc.titleInflammation: what's there and what's new?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleApplied Sciencespt_PT
person.familyNameCalhelha
person.familyNameHeleno
person.familyNameCarocho
person.familyNameBarros
person.givenNameRicardo C.
person.givenNameSandrina A.
person.givenNameMárcio
person.givenNameLillian
person.identifierawbWiiMAAAAJ&hl
person.identifier469085
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person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0001-7224-1098
person.identifier.orcid0000-0002-8978-4547
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridJ-2172-2014
person.identifier.ridL-5951-2014
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id30067731800
person.identifier.scopus-author-id52463229800
person.identifier.scopus-author-id35236343600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscoverye89b5bf5-d315-49b6-871e-fa8eb6030676

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