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Genome-wide scans detected signatures of selection in genes related with vision, xenobiotic metabolism, and immunity in the Iberian honey bee genome

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dc.contributor.authorChávez-Galarza, Julio
dc.contributor.authorHenriques, Dora
dc.contributor.authorJohnston, J. Spencer
dc.contributor.authorRufino, José
dc.contributor.authorPinto, M. Alice
dc.date.accessioned2013-10-28T11:15:43Z
dc.date.available2013-10-28T11:15:43Z
dc.date.issued2013
dc.description.abstractGenome-wide scan approaches to detect signatures of selection have become popular tools to study local adaptation at the molecular level and single nucleotide polymorphisms (SNPs) are seemingly the most appropriate marker for that endeavor. SNPs (i) provide a genome-wide coverage, (ii) generate high quality data, (iii) are suitable for automated high throughput technologies allowing genotyping of hundreds to thousands of loci in many individuals, and (iv) are commonly observed in functional genes. In this work, a total of 711 individuals of A. m. iberiensis were collected in 23 sites across three north-south transepts in the Iberian Peninsula. This collection was genotyped for 383 SNPs using the GoldenGate assay of Illumina. Then, the SNP dataset was examined in search for the footprints of selection with the following five different methods: (i) coalescence - LOSITAN and ARLEQUIN, (ii) Bayesian - BAYESFST and BAYESCAN, and (iii) Spatial Analysis - matSAM. These methods identified 10 loci exhibiting strong selection signal. The 10 loci were then located in the honey bee genome and their putative functions were determined using the honey bee genomic resources. The 10 loci were mapped to putative genes with diverse biological functions, which included vision, detoxification metabolism, and immunity.por
dc.description.sponsorshipFundação para a Ciência e Tecnologiapor
dc.identifier.citationChavez-Galarza, Julio; Henriques, Dora; Johnston, John Spencer; Rufino, José; Pinto, M. Alice (2013). Genome-wide scans detected signatures of selection in genes related with vision, xenobiotic metabolism, and immunity in the Iberian honey bee genome. In 43º International Apicultural Congress Apimondia. Kiev, Ucraniapor
dc.identifier.urihttp://hdl.handle.net/10198/8942
dc.language.isoengpor
dc.peerreviewednopor
dc.relationPOPULATION GENOMICS AND LANDSCAPE GENETICS OF THE IBERIAN HONEY BEE APIS MELLIFERA IBERIENSIS
dc.subjectIberian honey beepor
dc.subjectApis mellifera iberiensispor
dc.subjectSNPspor
dc.subjectSelectionpor
dc.titleGenome-wide scans detected signatures of selection in genes related with vision, xenobiotic metabolism, and immunity in the Iberian honey bee genomepor
dc.typeconference poster
dspace.entity.typePublication
oaire.awardTitlePOPULATION GENOMICS AND LANDSCAPE GENETICS OF THE IBERIAN HONEY BEE APIS MELLIFERA IBERIENSIS
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FBIA-BEC%2F099640%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F68682%2F2010/PT
oaire.citation.conferencePlaceKiev, Ucraniapor
oaire.citation.title43º International Apicultural Congress Apimondiapor
oaire.fundingStream5876-PPCDTI
person.familyNameHenriques
person.familyNameRufino
person.familyNamePinto
person.givenNameDora
person.givenNameJosé
person.givenNameM. Alice
person.identifier.ciencia-id291F-986F-07DA
person.identifier.ciencia-idC414-F47F-6323
person.identifier.ciencia-idF814-A1D0-8318
person.identifier.orcid0000-0001-7530-682X
person.identifier.orcid0000-0002-1344-8264
person.identifier.orcid0000-0001-9663-8399
person.identifier.scopus-author-id55761737300
person.identifier.scopus-author-id55947199100
person.identifier.scopus-author-id8085507800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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