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Antioxidant activity of decoctions of Centaurea paniculata L. and Helichrysum stoechas L. Moench

dc.contributor.authorBarroso, Marisa
dc.contributor.authorFernandes, Ângela
dc.contributor.authorCarvalho, Ana Maria
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2013-09-09T14:04:03Z
dc.date.available2013-09-09T14:04:03Z
dc.date.issued2013
dc.description.abstractEthnobotanical surveys conducted in Northeastern Portugal have documented the use of Decoctions prepared with flowering aerial parts of Centaurea paniculata L. (starthistles, knapweeds; port. escalabiosa) for inflammation and Helichrysum stoechas (L.) Moench (shrubby everlasting; port. douradinha) for the respiratory system and to reduce fever [1], from the Asteraceae botanical family. Although antioxidant properties of those plants have been investigated [2-4], there are no reports on its most used form, the decoction. Therefore, in the present work, decoctions of inflorescences and leafy flowering stems of the two mentioned species were prepared and submitted to evaluation of antioxidant potential. Four different in vitro assays were performed: scavenging effects on DPPH (2,2-diphenyl-1-picrylhydrazyl) radicals, reducing power (measured in Folin Ciocalteu and ferricyanide Prussian blue assays), inhibition of 13-carotene bleaching and inhibition of lipid peroxidation in brain cell homogenates by TBARS (thiobarbituric acid reactive substances) assay. Thedecoction of H. stoechas revealed higher antioxidant activity (lower EC50 values) than C. paniculata in all the tested assays. Data obtained could provide scientific evidence for some folk uses in the treatment of diseases related to the production of reactive species and oxidative stress, but further experiments are required to explore the mechanisms of action.por
dc.description.sponsorshipFCT (Portugal) for financial support to the research centre CIMO (PEst-OE/AGR/UI0690/201 1) and A. Fernandes grant (SFRH/BD/76019/2011 ).por
dc.identifier.citationBarroso, Marisa; Fernandes, Ângela; Carvalho, Ana Maria; Ferreira, Isabel C.F.R. (2013). Antioxidant activity of decoctions of Centaurea paniculata L. and Helichrysum stoechas L. Moench. In 1st Symposium on Medicinal Chemistry. Bragapor
dc.identifier.urihttp://hdl.handle.net/10198/8681
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationStrategic Project - UI 690 - 2011-2012
dc.titleAntioxidant activity of decoctions of Centaurea paniculata L. and Helichrysum stoechas L. Moenchpor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F76019%2F2011/PT
oaire.citation.conferencePlaceBraga, Portugalpor
oaire.citation.title1st Symposium on Medicinal Chemistry of University of Minhopor
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamSFRH
person.familyNameFernandes
person.familyNameCarvalho
person.familyNameFerreira
person.givenNameÂngela
person.givenNameAna Maria
person.givenNameIsabel C.F.R.
person.identifierID G-7399-2011
person.identifier144781
person.identifier.ciencia-id2015-0434-AE7C
person.identifier.ciencia-idD31A-35AF-E2A9
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-0157-9873
person.identifier.orcid0000-0001-5508-5935
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id20336503900
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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