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Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis

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dc.contributor.authorPereira, Olívia R.
dc.contributor.authorAfonso, Andrea Luísa Fernandes
dc.contributor.authorCardoso, Susana M.
dc.date.accessioned2016-09-26T15:19:53Z
dc.date.available2016-09-26T15:19:53Z
dc.date.issued2016
dc.description.abstractSalvia species are used worldwide for medicine purposes. In general, these medicinal plants have high amounts of flavonoids and phenolic acids, that are thought to be closely related to their health properties [1,2]. In this work, the aerial parts of Salvia farinacea, Salvia mexico, Salvia greggii and Salvia officinalis were extracted with hot water [3]. Extracts were evaluated for their total phenolic content by an adaptation of the Folin-Ciocalteu method and further analysed by high performance liquid chromatography associated with electrospray mass spectrometry (HPLC-DAD-ESI-MSn) in the negative ion mode [4], in order to identify their individual phenolic constituents. The aqueous extracts of S. farinacea, S. mexico, S. officinalis and S. greggii contained, respectively, 106±13, 159±38, 175±46 and 136±1 μg GAE/mg of total phenolics. These four species were characterized by a clear prevalence of caffeic acid derivatives, in particular of rosmarinic acid (MW 360), that is generally the most abundant phenolic compound in Salvia species [2,3]. In addition, S. mexico and S. officinalis contained moderate amounts of salvianolic acid B (MW 718). Among these two, S. mexico was richer in O-caffeoylquinic acid (MW 354), while the latter presented high amounts of salvianolic acid K (MW 556) and moderate amounts of its structural isomer. All the extracts were enriched in flavones: S. farinacea and S. officinalis contained high amounts of luteolin-O-glucuronide while S. mexico contained luteolin-C-glucoside with respective characteristic mass spectrometry fragmentation pattern m/z at 461→285 and m/z at 447→357, 327. Similarly, S. greggii extract presented high content of luteolin-7-O-glucoside ([M-H]− at m/z 447→ 285) and luteolin-C-glucoside and moderate quantities of apigenin-C-hexoside ([M-H]− at m/z 431→341, 311). Further studies are being undertaken in order to understand the contribution of these phenolic constituents in the biological activities of Salvia plants.pt_PT
dc.identifier.citationPereira, Olívia R.; Afonso, Andrea F.; Cardoso, Susana M. (2016). Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis. In 6th International Congress of Aromatic and Medicinal Plants. Coimbra. p. 192-192. ISBN 978-989-95050-1-8pt_PT
dc.identifier.issn978-989-95050-1-8
dc.identifier.urihttp://hdl.handle.net/10198/13299
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherUniversidade de Coimbra, Faculdade de Farmácia Universidade de Coimbrapt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSalviapt_PT
dc.subjectLamiaceaept_PT
dc.subjectPhenolic characterizationpt_PT
dc.subjectCaffeic acid derivativespt_PT
dc.titlePhenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalispt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceCoimbrapt_PT
oaire.citation.startPage192pt_PT
oaire.citation.title6th International Congress of Aromatic and Medicinal Plants (CIPAM 2016) Book of Abstractspt_PT
person.familyNamePereira
person.familyNameAfonso
person.givenNameOlívia R.
person.givenNameAndrea Luísa Fernandes
person.identifier145216
person.identifier.ciencia-idB312-AF21-D2FA
person.identifier.ciencia-id9C1D-41E7-9BBF
person.identifier.orcid0000-0002-6275-3134
person.identifier.orcid0000-0002-8858-1617
person.identifier.ridH-1049-2014
person.identifier.scopus-author-id52264387000
person.identifier.scopus-author-id36766901000
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicatione8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isAuthorOfPublicationaf7d647c-f5a6-48f7-afcf-6307c3677b1d
relation.isAuthorOfPublication.latestForDiscoverye8fdab9a-3ad6-47e6-b90c-7a37aabcb453

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