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Monitoring of ochratoxin a exposure of the Portuguese population through a nationwide urine survey – Winter 2007

2010Journal article Restricted access
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dc.contributor.authorDuarte, S.C.
dc.contributor.authorBento, J.M.V.
dc.contributor.authorPena, A.
dc.contributor.authorLino, C.M.
dc.contributor.authorDelerue-Matos, Cristina
dc.contributor.authorOliva-Teles, T.
dc.contributor.authorMorais, S.
dc.contributor.authorCorreia, Manuela
dc.contributor.authorOliveira, Beatriz
dc.contributor.authorAlves, M. Rui
dc.contributor.authorPereira, J.A.
dc.date.accessioned2011-01-14T10:23:19Z
dc.date.available2011-01-14T10:23:19Z
dc.date.issued2010
dc.description.abstractOchratoxin A (OTA) is a mycotoxin produced by a variety of fungi, such as Penicillium verrucosum and Aspergillium spp., which has been found to have a wide number of potentially deadly toxic effects, and can enter the human organism through a variety of means. It then finds its way into the bloodstream and, after a lengthy process, is eventually excreted through the urine. It can thus be detected in its original form not only in blood samples but also in this biological medium. As such, and in an attempt to evaluate the exposure of the Portuguese population to this mycotoxin, morning urine samples were collected during the Winter of 2007, from each of five geographically distinct Portuguese locations — Bragança, Porto, Coimbra, Alentejo, and Algarve — and subjected to extraction by immunoaffinity columns and to OTA quantification through liquid chromatography coupled with fluorescence detection. Prevalent incidence was higher than 95% with Coimbra being the exception (incidence of 73.3%). In nearly all locations, the OTA content of most samples was found to be above the limit of quantification (LOQ) of 0.008 ng/ml. Indeed, excluding Coimbra, with an OTA content level of 0.014 ng/ml, all regions featured content values over 0.021 ng/ml.por
dc.description.sponsorshipFCTpor
dc.identifier.citationDuarte, S.; Bento, J.; Pena, A.; Lino, C.M.; Delerue-Matos, C.; Oliva-Teles, T.; Morais, S.; Correia; M.; Oliveira, M.B.P.P.; Alves, M.R.; Pereira, J.A. (2010). Monitoring of ochratoxin A exposure of the Portuguese population through a nationwide urine survey – Winter 2007. Science of the Total Environment. ISSN 0048-9697. 408:5, p. 1195-1198por
dc.identifier.doi10.1016/j.scitotenv.2009.11.048
dc.identifier.issn0048-9697
dc.identifier.urihttp://hdl.handle.net/10198/3114
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.subjectOchratoxin Apor
dc.subjectUrinepor
dc.subjectNational surveypor
dc.subjectPortugalpor
dc.subjectLC-FDpor
dc.titleMonitoring of ochratoxin a exposure of the Portuguese population through a nationwide urine survey – Winter 2007por
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FAGR-ALI%2F65528%2F2006/PT
oaire.citation.endPage1198por
oaire.citation.issue408(5)por
oaire.citation.startPage1195por
oaire.citation.titleScience of the Total Environmentpor
oaire.fundingStream5876-PPCDTI
person.familyNamePereira
person.givenNameJosé Alberto
person.identifier.ciencia-id611F-80B2-A7C1
person.identifier.orcid0000-0002-2260-0600
person.identifier.ridL-6798-2014
person.identifier.scopus-author-id57204366348
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication7932162e-a2da-4913-b00d-17babbe51857
relation.isAuthorOfPublication.latestForDiscovery7932162e-a2da-4913-b00d-17babbe51857
relation.isProjectOfPublication430a3a4c-6ece-4958-b3ee-3c80a40c4b5b
relation.isProjectOfPublication.latestForDiscovery430a3a4c-6ece-4958-b3ee-3c80a40c4b5b

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