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Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography

dc.contributor.authorArafah, Rami
dc.contributor.authorRibeiro, António E.
dc.contributor.authorRodrigues, Alírio
dc.contributor.authorPais, Luís S.
dc.date.accessioned2023-02-01T10:03:52Z
dc.date.available2023-02-01T10:03:52Z
dc.date.issued2021
dc.description.abstractThe separation and purification of high added value products by liquid chromatography is a very popular technique. The development of more stable and efficient stationary phases, together with the design of innovative and more flexible separation processes, enhanced the use of chromatographic processes, particularly at preparative and industrial scales through fixedbed and simulated moving bed (SMB) technologies. Fixed-bed and SMB techniques are more and more used in the separation of a wide range of products for the pharmaceutical, fine chemistry, biotechnology and food industries. In this context, one of the actual main challenges concerns the design and optimization of these chromatographic processes for challenging multicomponent separations. This includes the development of new and innovative chromatographic processes, combining different design strategies and modes of operation, with different types of stationary and mobile phases.pt_PT
dc.description.sponsorshipThis work was financially supported by: Base Funding - UIDB/00690/2020 of CIMO - Centro de Investigação de Montanha - funded by national funds through FCT/MCTES (PIDDAC), and Base Funding - UIDB/50020/2020 of the Associate Laboratory LSRE-LCM - funded by national funds through FCT/MCTES (PIDDAC). This work is also a result of: Project - Advanced Industrial Processes and -01- 0145-FEDER-000006, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). Rami S. Arafah is supported by a PhD Grant of Fundação para a Ciência e a Tecnologia (SFRH/BD/137966/2018).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationArafah, Rami; Ribeiro, António E.; Rodrigues, Alírio; Pais, Luís S. (2022). Complete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatography. In Alexandra Pinto; Ana Isabel Moreira; Ana Teresa Cerdeira; André Torres Pinto; Cláudio Rocha; Isabel Fernandes; Maria Amélia Barros; Maria João Romeu (Eds.) 4th Symposium on Chemical and Biological Engineering. Portopt_PT
dc.identifier.isbn978-972-752-282-8
dc.identifier.urihttp://hdl.handle.net/10198/26716
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFEUP Ediçõespt_PT
dc.relationMountain Research Center
dc.relationLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials
dc.relationMulticomponent chiral separation by preparative and simulated moving bed chromatography
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSMBpt_PT
dc.subjectChromatographypt_PT
dc.subjectNadalolpt_PT
dc.subjectStereoisomerspt_PT
dc.subjectResearch Subject Categories::TECHNOLOGYpt_PT
dc.titleComplete separation of the quaternary mixture of nadolol stereoisomers using preparative and simulated moving bed chromatographypt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardTitleLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials
oaire.awardTitleMulticomponent chiral separation by preparative and simulated moving bed chromatography
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50020%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_NORTE/SFRH%2FBD%2F137966%2F2018/PT
oaire.citation.conferencePlacePortopt_PT
oaire.citation.endPage186pt_PT
oaire.citation.startPage185pt_PT
oaire.citation.title4th Symposium on Chemical and Biological Engineeringpt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPOR_NORTE
person.familyNameArafah
person.familyNameRibeiro
person.familyNamePais
person.givenNameRami
person.givenNameAntónio E.
person.givenNameLuís S.
person.identifier.ciencia-idAB16-ECBF-B886
person.identifier.ciencia-id3211-D5B0-870D
person.identifier.ciencia-id421E-0CCD-A84F
person.identifier.orcid0000-0002-7743-4988
person.identifier.orcid0000-0003-4569-7887
person.identifier.orcid0000-0002-3000-2862
person.identifier.scopus-author-id57151342900
person.identifier.scopus-author-id23390701300
person.identifier.scopus-author-id6603930478
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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