Repository logo
 
Publication

Health-promoting effects of Thymus herba-barona, Thymus pseudolanuginosus, and Thymus caespititius decoctions

2017Journal article Open access
Simple item page
dc.contributor.authorAfonso, Andrea Luísa Fernandes
dc.contributor.authorPereira, Olívia R.
dc.contributor.authorNeto, Rodrigo
dc.contributor.authorSilva, Artur
dc.contributor.authorCardoso, Susana M.
dc.date.accessioned2018-01-25T10:00:00Z
dc.date.accessioned2018-02-02T10:39:44Z
dc.date.available2018-01-25T10:00:00Z
dc.date.available2018-02-02T10:39:44Z
dc.date.issued2017
dc.description.abstractThymus herba-barona, Thymus pseudolanuginosus, and Thymus caespititius decoctions were screened for their phenolic constituents, along with their potential antioxidant, anti-inflammatory, and antibacterial activities. The total phenolic compounds in the extracts of the three plants ranged from 236.0 ± 26.6 mgGAE/g (T. caespititus) to 293.0 ± 30.5 mgGAE/g of extract (T. pseudolanuginosus), being particularly rich in caffeic acid derivatives, namely rosmarinic acid and its structural isomers, as well as flavones, such as luteolin-O-glucuronide. The T. pseudolanuginosus extract presented the best DPPH radical scavenging ability (EC 50 = 10.9 ± 0.7 µg/mL), a high reducing power (EC 50 = 32.2 ± 8.2 µg/mL), and effectively inhibited the oxidation of β-carotene (EC 50 = 2.4 ± 0.2 µg/mL). The extracts also showed NO· scavenging activity close to that of ascorbic acid, and thus might be useful as anti-inflammatory agents. In addition, they exhibited antibacterial activity against gram-negative and gram-positive bacteria. Staphylococcus aureus strains were the most sensitive bacteria to thyme extracts, with minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.6–3.5 mg/mL. Overall, this work is an important contribution for the phytochemical characterization and the potential antioxidant, anti-inflammatory, and antimicrobial activities of these three Thymus species, which have been poorly explored.en_EN
dc.description.sponsorshipThe authors acknowledge to the Foundation for Science and Technology (FCT), the European Union, the National Strategic Reference Framework (QREN), the European Regional Development Fund (FEDER), and Operational Programme Competitiveness Factors (COMPETE), for funding the Organic Chemistry Research Unit (QOPNA) (project PEst-C/QUI/UI0062/2013; FCOMP-01-0124-FEDER-037296).
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationAfonso, Andrea F.; Pereira, Olívia R.; Neto, Rodrigo T.; Silva, Artur M.S.; Cardoso, Susana M. (2017). Health-promoting effects of Thymus herba-barona, Thymus pseudolanuginosus, and Thymus caespititius decoctions. International Journal of Molecular Sciences. ISSN 1661-6596. 18, p. 1-14en_EN
dc.identifier.doi10.3390/ijms18091879en_EN
dc.identifier.issn1661-6596
dc.identifier.urihttp://hdl.handle.net/10198/15505
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.subjectAnti-inflammatoryen_EN
dc.subjectAntimicrobial activityen_EN
dc.subjectAntioxidanten_EN
dc.subjectAntiradicalaren_EN
dc.subjectLC-MSen_EN
dc.subjectMass spectrometryen_EN
dc.subjectPhenolicen_EN
dc.subjectThymeen_EN
dc.subjectThymusen_EN
dc.titleHealth-promoting effects of Thymus herba-barona, Thymus pseudolanuginosus, and Thymus caespititius decoctionsen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/COMPETE/PEst-C%2FQUI%2FUI0062%2F2013/PT
oaire.fundingStreamCOMPETE
person.familyNameAfonso
person.familyNamePereira
person.givenNameAndrea Luísa Fernandes
person.givenNameOlívia R.
person.identifier145216
person.identifier.ciencia-id9C1D-41E7-9BBF
person.identifier.ciencia-idB312-AF21-D2FA
person.identifier.orcid0000-0002-8858-1617
person.identifier.orcid0000-0002-6275-3134
person.identifier.ridH-1049-2014
person.identifier.scopus-author-id36766901000
person.identifier.scopus-author-id52264387000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublicationaf7d647c-f5a6-48f7-afcf-6307c3677b1d
relation.isAuthorOfPublicatione8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isAuthorOfPublication.latestForDiscoverye8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isProjectOfPublicationc6cfbfe6-0981-49d7-8a9b-41f9904a0330
relation.isProjectOfPublication.latestForDiscoveryc6cfbfe6-0981-49d7-8a9b-41f9904a0330

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
1.pdf
Size:
580.56 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.75 KB
Format:
Plain Text
Description:
Download

Collections

CIMO - Artigos em Revistas Indexados à WoS/Scopus