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The oomycete P. cinnamomi, the causal agent of Castanea sativa ink disease, is one of the most distinctive species of Phytophthora genus, and has been associated with the decline of several forest, ornamental and fruit trees and shrubs, causing enormous economic losses worldwide.
Phytophthora cell walls are composed of glucanase and have no chitin. Production of glucanase inhibitor proteins (G IPs) by Phytophthora species are thought to provide them a counter-defense against plant hosts P- l ,3-g11lcanascs (Rose el aI., 2002), that otherwise would degrade these pathogen cell walls. GIPs belongs to the chymotrypsin family of serine proteases but are catalytically nonfunctional because one or more residues of the essential catalytic triad are absent.
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Carvalho, Marisa; Meirinho, Sofia; Jorge, Lurdes; Dominguez, Angél; Choupina, Altino (2008). Identification of a Phytophthora cinnamomi glucanase inhibitor protein: a molecular factor associated to infection mechanism. In XVI Congresso Nacional de Bioquímica. Ponta Delgada