Publication
Levels of urinary biomarkers of exposure and potential genotoxic risks in firefighters
| dc.contributor.author | Oliveira, Marta | |
| dc.contributor.author | Delerue-Matos, Cristina | |
| dc.contributor.author | Morais, Simone | |
| dc.contributor.author | Slezakova, Klara | |
| dc.contributor.author | Pereira, Maria do Carmo | |
| dc.contributor.author | Fernandes, Adília | |
| dc.contributor.author | Costa, Solange | |
| dc.contributor.author | Teixeira, João Paulo Fernandes | |
| dc.date.accessioned | 2019-04-10T13:24:30Z | |
| dc.date.available | 2019-04-10T13:24:30Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | This study characterizes the levels of six urinary monohydroxyl-polycyclic aromatic hydrocarbons in Portuguese firefighters directly involved in firefighting activities. Median concentrations of urinary total monohydroxyl-PAHs were predominantly higher in exposed subjects comparatively with non-exposed firefighters (3.12 versus 1.59 mu mol/mol creatinine, respectively). Urinary 1-hydroxynaphthalene and 1-hydroxyacenaphthene were the most predominant metabolites (87-90% of total monohydroxyl-PAHs), being followed by 2-hydroxylfluorene (2.4-6.3%), 1-hydroxyphenanthrene (4.1-5.4%), and 1-hydroxypyrene (2.0-2.6%). Firefighters who were directly involved in fire combat activities presented increased percentages of DNA damage (9.85 versus 10.9%; p <= 0.01) and oxidative stress (0 versus 2.14% TDNA; p <= 0.01) comparatively with non-exposed subjects, thus revealing the impact of fires on the health of exposed firefighters. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Oliveira, M.; Delerue-Matos, C; Morais, S.; Slezakova, K; Pereira, M.C.; Fernandes, Adília; Costa, Solange.; Teixeira, J.P (2018). Levels of urinary biomarkers of exposure and potential genotoxic risks in firefighters risks. In 6th International Symposium on Occupational Safety and Hygiene (SHO). Guimaraes, Portugal. p. 267–271. ISBN: 978-1-138-54203-7 | pt_PT |
| dc.identifier.isbn | 978-1-138-54203-7 | |
| dc.identifier.uri | http://hdl.handle.net/10198/19240 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Taylor & Francis Group | pt_PT |
| dc.relation | Indoor and Outdoor Exposure to Ultrafine Particles: the Implications for Public Health | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Polycyclic aromatic-hydrocarbons | pt_PT |
| dc.subject | Occupational-exposure | pt_PT |
| dc.subject | Hydroxypyrene | pt_PT |
| dc.subject | Metabolites | pt_PT |
| dc.title | Levels of urinary biomarkers of exposure and potential genotoxic risks in firefighters | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Indoor and Outdoor Exposure to Ultrafine Particles: the Implications for Public Health | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F50006%2F2013/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F105100%2F2014/PT | |
| oaire.citation.conferencePlace | Guimarães | pt_PT |
| oaire.citation.endPage | 271 | pt_PT |
| oaire.citation.startPage | 267 | pt_PT |
| oaire.citation.title | Occupational Safety and Hygiene VI | pt_PT |
| oaire.fundingStream | 5876 | |
| oaire.fundingStream | OE | |
| person.familyName | Fernandes | |
| person.givenName | Adília | |
| person.identifier.ciencia-id | 0514-76CD-8CCF | |
| person.identifier.orcid | 0000-0003-1658-4509 | |
| person.identifier.rid | V-8399-2017 | |
| person.identifier.scopus-author-id | 56489572200 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isAuthorOfPublication | bdfceda8-18d6-4b63-b6f9-d3870cd0dbb0 | |
| relation.isAuthorOfPublication.latestForDiscovery | bdfceda8-18d6-4b63-b6f9-d3870cd0dbb0 | |
| relation.isProjectOfPublication | 40f15c30-b6e8-4474-ae1d-d7256c7af84e | |
| relation.isProjectOfPublication | 004426ea-ac5d-41e2-8698-98ec0c0bdd50 | |
| relation.isProjectOfPublication.latestForDiscovery | 40f15c30-b6e8-4474-ae1d-d7256c7af84e |