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Searching for signatures of selection in Iberian honey bee (Apis mellifera iberiensis) using whole genome sequences

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dc.contributor.authorHenriques, Dora
dc.contributor.authorWallberg, Andreas
dc.contributor.authorChávez-Galarza, Julio
dc.contributor.authorCosta, Filipe Oliveira
dc.contributor.authorRufino, José
dc.contributor.authorWebster, Matthew T.
dc.contributor.authorPinto, M. Alice
dc.date.accessioned2018-03-28T09:01:54Z
dc.date.available2018-03-28T09:01:54Z
dc.date.issued2015
dc.description.abstractThe Iberian Peninsula comprises a diverse set of habitats. It was an important glacial refugium during the Pleistocene and has served as a bridge for populations migrating between Africa and Europe, resulting in a complex mix of ancestry and diversity. The Iberian honey bee (A. m. iberiensis) is no exception and has been the subject of numerous incongruent population genetic surveys. Recent mtDNA and SNP analyses indicate a steep northeastern-southwestern cline of African ancestry along the peninsula, which has been explained by selection. Advances in DNA sequencing technology and computational tools provide unprecedented opportunities to study demography, search for signatures of selection across the genome and illuminate its role in shaping genomic diversity. We used Illumina technology to sequence the whole genomes of 86 Iberian honeybees, collected across three longitudinal transects in the Iberian Peninsula and spanning semi-arid climates in the southeastern peninsula to oceanic in the North-West. The dataset was first analyzed for FST-outliers, CLR (composite-likelihood ratio) and EHH (Extended Haplotype Homozygosity) methods were further deployed to evaluate polymorphisms implicated in local adaptation and possibly in the response to human- mediated environmental changes, including known and novel variants in genes related to behavior, vision, xenobiotic detoxification and immune response.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationHenriques, Dora; Wallberg, Andreas; Rufino, José; Chávez-Galarza, Julio; Costa, Filipe; Webster, Mathew; Pinto, M. Alice (2015). Searching for signatures of selection in Iberian honey bee (Apis mellifera iberiensis) using whole genome sequences. In Congress of the European Society for Evolutionary Biology. Lausanne, Switzerlandpt_PT
dc.identifier.urihttp://hdl.handle.net/10198/16600
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherUniversite de Lausannept_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleSearching for signatures of selection in Iberian honey bee (Apis mellifera iberiensis) using whole genome sequencespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceLausannept_PT
oaire.citation.endPage252pt_PT
oaire.citation.startPage252pt_PT
oaire.citation.titleAbstract List of the Congress of the European Society for Evolutionary Biology (ESEB 2015),pt_PT
person.familyNameHenriques
person.familyNameRufino
person.familyNamePinto
person.givenNameDora
person.givenNameJosé
person.givenNameM. Alice
person.identifier.ciencia-id291F-986F-07DA
person.identifier.ciencia-idC414-F47F-6323
person.identifier.ciencia-idF814-A1D0-8318
person.identifier.orcid0000-0001-7530-682X
person.identifier.orcid0000-0002-1344-8264
person.identifier.orcid0000-0001-9663-8399
person.identifier.scopus-author-id55761737300
person.identifier.scopus-author-id55947199100
person.identifier.scopus-author-id8085507800
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationd2abd09f-a90c-4cfb-9a60-7fc32f56184d
relation.isAuthorOfPublication1e24d2ce-a354-442a-bef8-eebadd94b385
relation.isAuthorOfPublication0667fe04-7078-483d-9198-56d167b19bc5
relation.isAuthorOfPublication.latestForDiscoveryd2abd09f-a90c-4cfb-9a60-7fc32f56184d

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