Logo do repositório
 
Publicação

Optimised model microcapsules of Arabic gum and gelatin a for functional cosmetic applications: From formulation to scale-up using a mesostructured reactor

2025Artigo científico Acesso aberto
Ver registo simples
dc.contributor.authorKessler, Júlia C.
dc.contributor.authorMartins, Isabel M.
dc.contributor.authorManrique, Yaidelin A.
dc.contributor.authorLopes, José Carlos B.
dc.contributor.authorRodrigues, Alírio
dc.contributor.authorBarreiro, M.F.
dc.contributor.authorDias, Madalena M.
dc.date.accessioned2025-02-10T11:17:53Z
dc.date.available2025-02-10T11:17:53Z
dc.date.issued2025
dc.description.abstractMicrocapsules were developed using Arabic gum and gelatin A through complex coacervation, employing both batch and continuous production methods. Ingredients were chosen to encapsulate diverse hydrophobic core materials with functional properties tailored for cosmetic applications, such as those found in commercial hydrating creams, aiming to enhance their performance through microencapsulation. The formulation was optimised by systematically adjusting key parameters to balance the electrostatic and structural behaviour of the polymers, ensuring ideal encapsulation conditions. The optimised batch formulation (3.5:1 vol-to-volume ratio of core material to emulsifier, stirring at 9500 rpm for 2 min, and 10 % crosslinker concentration) resulted in spherical, multinuclear microcapsules with an average size of circa 60 μm, maintaining structural stability over 45 days. Encapsulation efficiency, defined as the percentage of core material successfully enclosed within the microcapsules relative to the initial amount used, reached up to 89 %. Transitioning to a continuous production method using the NETmix reactor further improved performance, achieving an encapsulation efficiency of 98 %. This was accomplished by performing the emulsification and polymer complexation steps under controlled Reynolds numbers of approximately 358 and 559, sustained over 2 and 4 minutes, respectively.pt_PT
dc.description.sponsorshipThis work was supported by national funds through FCT/MCTES (PIDDAC): LSRE-LCM, UIDB/50020/2020 (DOI: 10.54499/UIDB/ 50020/2020) and UIDP/50020/2020 (DOI: 10.54499/UIDP/50020/ 2020); ALiCE, LA/P/0045/2020 (DOI: 10.54499/LA/P/0045/2020); CIMO, UIDB/00690/2020 (DOI: 10.54499/UIDB/00690/2020) and UIDP/00690/2020 (DOI: 10.54499/UIDP/00690/2020); and LA SusTEC, LA/P/0007/2021 (DOI:10.54499/LA/P/0007/2020). Júlia Cristiê Kessler acknowledges her PhD scholarship (ref. 2020.06656.BD, DOI: 10.54499/2020.06656.BD) from FCT.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationKessler, Júlia C.; Martins, Isabel M.; Manrique, Yaidelin A.; Lopes, José Carlos B.; Rodrigues, Alírio E.; Barreiro, M. F.; Dias, Madalena M. (2025). Optimised model microcapsules of Arabic gum and gelatin a for functional cosmetic applications: From formulation to scale-up using a mesostructured reactor. Chemical Engineering Research and Design. ISSN 0263-8762. 215, p. 108-121pt_PT
dc.identifier.doi10.1016/j.cherd.2025.01.035pt_PT
dc.identifier.issn0263-8762
dc.identifier.urihttp://hdl.handle.net/10198/31151
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials
dc.relationLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials
dc.relationALICE - Associate Laboratory in Chemical Engineering
dc.relationMountain Research Center
dc.relationMountain Research Center
dc.relationAssociate Laboratory for Sustainability and Tecnology in Mountain Regions
dc.relationSupercritical extraction and NETmix technology to produce green and stabilized M. oleifera functional ingredients having in view cosmeceutical formulations
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectEncapsulationpt_PT
dc.subjectComplex coacervationpt_PT
dc.subjectArabic gum+gelatinept_PT
dc.subjectBatch mode optimisationpt_PT
dc.subjectContinuous mode scale-uppt_PT
dc.subjectNETmixpt_PT
dc.titleOptimised model microcapsules of Arabic gum and gelatin a for functional cosmetic applications: From formulation to scale-up using a mesostructured reactorpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/50020/2020
oaire.awardNumberUIDP/50020/2020
oaire.awardNumberLA/P/0045/2020
oaire.awardNumberUIDB/00690/2020
oaire.awardNumberUIDP/00690/2020
oaire.awardNumberLA/P/0007/2020
oaire.awardNumber2020.06656.BD
oaire.awardTitleLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials
oaire.awardTitleLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials
oaire.awardTitleALICE - Associate Laboratory in Chemical Engineering
oaire.awardTitleMountain Research Center
oaire.awardTitleMountain Research Center
oaire.awardTitleAssociate Laboratory for Sustainability and Tecnology in Mountain Regions
oaire.awardTitleSupercritical extraction and NETmix technology to produce green and stabilized M. oleifera functional ingredients having in view cosmeceutical formulations
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50020%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50020%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0045%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0007%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_NORTE/2020.06656.BD/PT
oaire.citation.endPage121pt_PT
oaire.citation.startPage108pt_PT
oaire.citation.titleChemical Engineering Research and Designpt_PT
oaire.citation.volume215pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPOR_NORTE
person.familyNameBarreiro
person.givenNameFilomena
person.identifier.ciencia-id3418-47D5-5746
person.identifier.orcid0000-0002-6844-333X
person.identifier.ridL-9802-2014
person.identifier.scopus-author-id57188719717
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication0391987c-ba90-488b-839a-153447ce1f0f
relation.isAuthorOfPublication.latestForDiscovery0391987c-ba90-488b-839a-153447ce1f0f
relation.isProjectOfPublication79ed495f-40dc-45d0-b98c-7e777db59e9b
relation.isProjectOfPublication75d8d4f7-ae07-4777-a9f1-3e833d96d5b4
relation.isProjectOfPublicationc6751eb9-1747-4136-89dc-b13cb8c17810
relation.isProjectOfPublication29718e93-4989-42bb-bcbc-4daff3870b25
relation.isProjectOfPublication0aac8939-28c2-46f4-ab6b-439dba7f9942
relation.isProjectOfPublication6255046e-bc79-4b82-8884-8b52074b4384
relation.isProjectOfPublication0f55349e-0580-402a-ad4f-77d8cec41b80
relation.isProjectOfPublication.latestForDiscovery0f55349e-0580-402a-ad4f-77d8cec41b80

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
Optimised_model_microcapsules.pdf
Tamanho:
13.9 MB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
1.75 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

CIMO - Artigos em Revistas Indexados à WoS/Scopus