Publication
Nepeta nuda tincture Vs. Listerine – who wins the battle against oral pathogens?
| dc.contributor.author | Smiljković, Marija | |
| dc.contributor.author | Dias, Maria Inês | |
| dc.contributor.author | Stojković, Dejan | |
| dc.contributor.author | Barros, Lillian | |
| dc.contributor.author | Bukvički, Danka | |
| dc.contributor.author | Ferreira, Isabel C.F.R. | |
| dc.contributor.author | Soković, Marina | |
| dc.date.accessioned | 2019-01-22T12:19:52Z | |
| dc.date.available | 2019-01-22T12:19:52Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Antimicrobial activity of Nepeta nuda L. (Lamiaceae) tincture and Listerine against a selected group of oral pathogenic microorganisms (4 bacterial species and 9 fungal strains) was explored. The activity of N. nuda tincture and Listerine to inhibit the formation of biofilm has been compared as well as their potential to demolish biofilm that is already established. Furthermore, based on in vitro experiments, the amount of N. nuda tincture and swishing time necessary for reaching better or equivalent antimicrobial effect as Listerine were predicted. Chemical constituents in N. nuda tincture regarding phenolic compounds were determined by LC-DAD/ESI-MSn. Both Listerine and N. nuda tincture possessed good antimicrobial potential, and acted on biofilms on two different developmental stages. When dealing with bacteria that have biofilm forming ability, N. nuda tincture would be highly recommended since it showed much better potential to inhibit formation of biofilms. For application via swishing, both mouthwashes should be used for 30 s when dealing with selected microorganisms in general and for 60 s (N. nuda tincture, 100 mg mL-1) when dealing with bacterial biofilms. Recommended volume of liquid for swishing is 20 mL. Chemical profiling showed rosmarinic acid and verminoside as the most dominant phenolic compounds present in the N. nuda tincture. So, who wins this battle? The authors could conclude that both mouthwashes stand shoulder to shoulder when it comes to exhibiting antimicrobial potential, and since Listerine has been in wide use for long time period, and it would be an attractive challenge to put some competition on the market. | pt_PT |
| dc.description.sponsorship | This work has been supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Grant No. 173032). The authors are grateful to the Foundation for Science and Technology (FCT) of Portugal and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2013) and L. Barros research contract. The authors are grateful to FEDER-Interreg España-Portugal programme for financial support through the project 0377_Iberphenol_6_E. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Smiljković, Marija; Dias, Maria Inês; Stojković, Dejan; Barros, Lillian; Bukvički, Danka; Ferreira, Isabel C.F.R.; Soković, Marina (2018). Nepeta nuda tincture Vs. Listerine – who wins the battle against oral pathogens? In 3rd International Conference on Plant Biology. Belgrado | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10198/18515 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Mouthwash | pt_PT |
| dc.subject | Oral microorganisms | pt_PT |
| dc.subject | Chemical constituents | pt_PT |
| dc.subject | Biofilms | pt_PT |
| dc.title | Nepeta nuda tincture Vs. Listerine – who wins the battle against oral pathogens? | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT | |
| oaire.citation.conferencePlace | Belgrado, Sérvia | pt_PT |
| oaire.citation.title | 3rd International Conference on Plant Biology | pt_PT |
| oaire.fundingStream | 5876 | |
| person.familyName | Dias | |
| person.familyName | Barros | |
| person.familyName | Ferreira | |
| person.givenName | Maria Inês | |
| person.givenName | Lillian | |
| person.givenName | Isabel C.F.R. | |
| person.identifier | 469085 | |
| person.identifier | 144781 | |
| person.identifier.ciencia-id | 2A13-4BE6-C7CF | |
| person.identifier.ciencia-id | 9616-35CB-D001 | |
| person.identifier.ciencia-id | 9418-CF95-9919 | |
| person.identifier.orcid | 0000-0001-8744-7814 | |
| person.identifier.orcid | 0000-0002-9050-5189 | |
| person.identifier.orcid | 0000-0003-4910-4882 | |
| person.identifier.rid | M-8242-2013 | |
| person.identifier.rid | J-3600-2013 | |
| person.identifier.rid | E-8500-2013 | |
| person.identifier.scopus-author-id | 54388787000 | |
| person.identifier.scopus-author-id | 35236343600 | |
| person.identifier.scopus-author-id | 36868826600 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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