Repository logo
 
Publication

Synergisms in antioxidant and anti-hepatocellular carcinoma activities of artichoke, milk thistle, and borututu syrups

2014Journal article Open access
Simple item page
dc.contributor.authorPereira, Carla
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorBarros, Lillian
dc.contributor.authorQueiroz, Maria João R.P.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2014-05-13T10:40:28Z
dc.date.available2014-05-13T10:40:28Z
dc.date.issued2014
dc.description.abstractArtichoke, borututu and milk thistle are three medicinal plants well-known for their capacity to prevent oxidative stress and many liver diseases. In a previous work, we reported the bioactivity of infusions and pills based on these plants; herein, the aim was to provide scientific information about the antioxidant and anti-hepatocellular carcinoma activities of syrups based on these medicinal plants and evaluate the synergism among the combined plants by using syrups based on the mixed plants or prepared form the combinations of individual species. The antioxidant activity was measured by radical scavenging activity, reducing power and lipid peroxidation inhibition, while the anti-hepatocellular carcinoma activity and the hepatotoxicity were evaluated using HepG2 human cell line and a primary culture of porcine liver cells, respectively. Milk thistle syrup proved to have the highest antioxidant activity in all the assayed methods, providing the best results either in single syrup or included in mixed syrups. Synergistic effects were the main interactions observed in the mixture of artichoke, borututu and milk thistle; mixing the syrups based on each single plant proved to be more efficient regarding antioxidant proposals than mixing plants in the same syrup. The latter was advantageous for anti-hepatocellular carcinoma activity.por
dc.identifier.citationPereira, Carla; Calhelha, Ricardo C.; Barros, Lillian; Queiroz, Maria-João R.P.; Ferreira, Isabel C.F.R. (2014). Synergisms in antioxidant and anti-hepatocellular carcinoma activities of artichoke, milk thistle, and borututu syrups. Industrial Crops and Products. ISSN 0926-6690. 52, p. 709-713por
dc.identifier.doi10.1016/j.indcrop.2013.11.050
dc.identifier.issn0926-6690
dc.identifier.urihttp://hdl.handle.net/10198/9502
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relationStrategic Project - UI 690 - 2011-2012
dc.subjectMedicinal plantspor
dc.subjectSyrupspor
dc.subjectHepG2por
dc.subjectSynergismpor
dc.titleSynergisms in antioxidant and anti-hepatocellular carcinoma activities of artichoke, milk thistle, and borututu syrupspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.citation.endPage713por
oaire.citation.startPage709por
oaire.citation.titleIndustrial Crops and Productspor
oaire.citation.volume52por
oaire.fundingStream6817 - DCRRNI ID
person.familyNamePereira
person.familyNameCalhelha
person.familyNameBarros
person.familyNameFerreira
person.givenNameCarla
person.givenNameRicardo C.
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier1415151
person.identifier469085
person.identifier144781
person.identifier.ciencia-idEF10-2739-2B70
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-0093-771X
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridK-1629-2016
person.identifier.ridJ-2172-2014
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id55627876424
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicatione07a8e12-52bb-47c5-bae7-41a5f648213b
relation.isAuthorOfPublication2d5d1a41-7561-4a01-871c-b4c97da35053
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscovery3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isProjectOfPublicationc59f09d4-9931-4f2e-babb-ef8bed998be7
relation.isProjectOfPublication.latestForDiscoveryc59f09d4-9931-4f2e-babb-ef8bed998be7

Files

Original bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
Xaropes_ICP_Revised.pdf
Size:
196.99 KB
Format:
Adobe Portable Document Format
Download
No Thumbnail Available
Name:
1-s2.0-S0926669013006766-main.pdf
Size:
376.44 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.73 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Artigos em Revistas Indexados à WoS/Scopus