Epoxidation studies of 2-styrylchromones using Jacobsen’s catalyst and hydrogen peroxide and iodosylbenzene as oxidants

Santos, Clementina M.M.; Silva, Artur; Cavaleiro, José; Patonay, Támas; Lévai, Albert

http://hdl.handle.net/10198/3923

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Authors

Santos, Clementina M.M.

Abstract(s)

The epoxidation of 2-styrylchromones 2a-h using Jacobsen’s Mn(III)[salen] complex 1 as catalyst is reported for the first time. Several studies were performed using both hydrogen peroxide and iodosylbenzene as oxidants, in order to obtain the α,β-epoxy-2-styrylchromones 3a-h regioselectively. Due to the low reactivity of the substrates and the highly unstable character of the formed epoxides, reactions should be interrupted at lower conversions to obtain acceptable yields, especially when hydrogen peroxide is used.

Keywords

2-Styrylchromones Jacobsen catalyst Epoxidation Iodosylbenzene Hydrogen peroxide

URI

http://hdl.handle.net/10198/3923

Citation

Santos, Clementina; Silva, Artur; Cavaleiro, José; Patonay, Támas; Lévai, Albert (2006). Epoxidation studies of 2-styrylchromones using Jacobsen’s catalyst and hydrogen peroxide and iodosylbenzene as oxidants. Journal of Heterocyclic Chemistry. ISSN 0022-152X. 43:5, p. 1319-1326