Repository logo
 
Publication

A rapid and low-cost nonlithographic method to fabricate biomedical microdevices for blood flow analysis

2015Journal article Open access
Simple item page
dc.contributor.authorPinto, Elmano
dc.contributor.authorFaustino, Vera
dc.contributor.authorRodrigues, Raquel Oliveira
dc.contributor.authorPinho, Diana
dc.contributor.authorGarcia, Valdemar
dc.contributor.authorMiranda, João Mário
dc.contributor.authorLima, Rui A.
dc.date.accessioned2015-06-19T09:51:01Z
dc.date.available2015-06-19T09:51:01Z
dc.date.issued2015
dc.description.abstractMicrofluidic devices are electrical/mechanical systems that offer the ability to work with minimal sample volumes, short reactions times, and have the possibility to perform massive parallel operations. An important application of microfluidics is blood rheology in microdevices, which has played a key role in recent developments of lab-on-chip devices for blood sampling and analysis. The most popular and traditional method to fabricate these types of devices is the polydimethylsiloxane (PDMS) soft lithography technique, which requires molds, usually produced by photolithography. Although the research results are extremely encouraging, the high costs and time involved in the production of molds by photolithography is currently slowing down the development cycle of these types of devices. Here we present a simple, rapid, and low-cost nonlithographic technique to create microfluidic systems for biomedical applications. The results demonstrate the ability of the proposed method to perform cell free layer (CFL) measurements and the formation of microbubbles in continuous blood flow.por
dc.description.sponsorshipPTDC/SAU-BEB/105650/2008, PTDC/SAU-ENB/116929/2010, EXPL/EMS-SIS/2215/2013 and scholarship SFRH/BD/89077/2012 and SFRH/BD/97658/2013 from FCT (Science and Technology Foundation), COMPETE, QREN and European Union (FEDER).por
dc.identifier.citationPinto, Elmano; Faustino, V.; Rodrigues, Raquel Oliveira; Pinho, Diana; Garcia, Valdemar; Miranda, João; Lima, R. (2015). A rapid and low-cost nonlithographic method to fabricate biomedical microdevices for blood flow analysis. Micromachines. ISSN 2072-666X. 6, p. 121-135por
dc.identifier.doi10.3390/mi6010121
dc.identifier.issn2072-666X
dc.identifier.urihttp://hdl.handle.net/10198/11879
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherMDPIpor
dc.relationBIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability
dc.relationMAGNETIC CARBON NANOSTRUCTURES AND STUDY OF THEIR TRANSPORT IN MICROFLUIDIC DEVICES FOR HYPERTHERMIA
dc.subjectLow cost biochipspor
dc.subjectNonlithographic techniquepor
dc.subjectXurographypor
dc.subjectBlood flowpor
dc.subjectBifurcationspor
dc.subjectMicrobubblespor
dc.titleA rapid and low-cost nonlithographic method to fabricate biomedical microdevices for blood flow analysispor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleBIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability
oaire.awardTitleMAGNETIC CARBON NANOSTRUCTURES AND STUDY OF THEIR TRANSPORT IN MICROFLUIDIC DEVICES FOR HYPERTHERMIA
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-BEB%2F105650%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-ENB%2F116929%2F2010/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/COMPETE/EXPL%2FEMS-SIS%2F2215%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F89077%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F97658%2F2013/PT
oaire.citation.endPage135por
oaire.citation.startPage121por
oaire.citation.titleMicromachinespor
oaire.citation.volume6por
oaire.fundingStream5876-PPCDTI
oaire.fundingStream5876-PPCDTI
oaire.fundingStreamCOMPETE
oaire.fundingStreamSFRH
person.familyNamePinho
person.familyNameGarcia
person.familyNameLima
person.givenNameDiana
person.givenNameValdemar
person.givenNameRui A.
person.identifier.ciencia-id5214-ED0C-35E8
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.orcid0000-0002-3884-6496
person.identifier.orcid0000-0002-3941-2438
person.identifier.orcid0000-0003-3428-637X
person.identifier.ridH-5157-2016
person.identifier.scopus-author-id18437397800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication02bf2dd9-33ed-4d87-b61d-ca39c51f8451
relation.isAuthorOfPublicationf9422279-4412-49c2-becd-1e696a8c5c4b
relation.isAuthorOfPublication7b50c499-8095-4f4f-8b1b-fa7388e4ff62
relation.isAuthorOfPublication.latestForDiscovery7b50c499-8095-4f4f-8b1b-fa7388e4ff62
relation.isProjectOfPublication3897ce26-be5f-458d-829a-925628d3b9c7
relation.isProjectOfPublication0785b517-d2cf-4d92-b2e1-d45afee17273
relation.isProjectOfPublication7aa7bf1a-0dca-461e-90aa-9ca40cbedcb7
relation.isProjectOfPublicationa703ea48-10f3-42ed-867e-2aae71b722e8
relation.isProjectOfPublication95f49ee8-5b1f-45de-b818-d9334a4d8d0e
relation.isProjectOfPublication.latestForDiscovery7aa7bf1a-0dca-461e-90aa-9ca40cbedcb7

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
micromachines-06-00121.pdf
Size:
3 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESTiG - Artigos em Revistas Indexados à WoS/Scopus