Logo do repositório
 
Publicação

Genetic Diversity of Detoxification Genes in 18 Honey Bee Subspecies

2025Documento de conferência Acesso aberto
Ver registo simples
datacite.subject.fosCiências Agrárias::Biotecnologia Agrária e Alimentar
datacite.subject.fosCiências Naturais::Ciências da Terra e do Ambiente
datacite.subject.sdg04:Educação de Qualidade
datacite.subject.sdg13:Ação Climática
datacite.subject.sdg15:Proteger a Vida Terrestre
dc.contributor.authorLi, Fernanda
dc.contributor.authorBarbosa, Daniela
dc.contributor.authorBashir, Sana
dc.contributor.authorMoreira de Sá, Leandro
dc.contributor.authorYadró Garcia, Carlos A.
dc.contributor.authorRufino, José
dc.contributor.authorRosa-Fontana, Annelise
dc.contributor.authorVerbinnen, Gilles
dc.contributor.authorde Graaf, Dirk
dc.contributor.authorde Smet, Lina
dc.contributor.authorTaliadoros, Demetris
dc.contributor.authorWebster, Matthew
dc.contributor.authorPinto, M. Alice
dc.contributor.authorHenriques, Dora
dc.date.accessioned2026-02-13T14:20:05Z
dc.date.available2026-02-13T14:20:05Z
dc.date.issued2025
dc.description.abstractThe honey bees (Apis mellifera) is a key pollinator that is exposed to a wide array of xenobiotics, both natural (plant allelochemicals) and synthetic (pesticides), while foraging or through contaminated food within the hive. These compounds have both lethal and sub-lethal effects, impairing foraging activity and negatively affecting bee development and colony health. Similar to other insects, honey bees rely on detoxification pathways to metabolise xenobiotics into less toxic or more readily excretable forms. This process is a key mechanism underlying insecticide resistance and is influenced by genetic variation. Therefore, investigating polymorphisms in detoxification-related genes is a promising approach to predict species-specific responses to pesticide exposure. Five major gene families are involved in xenobiotic detoxification: cytochrome P450 monooxygenases (CYPs), carboxyl/cholinesterases (CCEs), glutathione Stransferases (GSTs), ATP-binding cassette transporters (ABCs), and uridine 5′-diphospho-glucuronosyltransferases (UGTs). In this study, we examined the genomic detoxification inventory of over 1,600 individuals representing 18 A. mellifera subspecies representing the four main evolutionary lineages. For each lineage and subspecies, single-nucleotide polymorphism (SNP) loci were identified within these genes, allele frequency and FST (fixation index) were calculated. Additionally, all variants were annotated to assess their potential impact on protein function. Findings from this study have the potential to inform breeding and conservation strategies by identifying populations more vulnerable to chemical stressors, ultimately supporting honey bee health in changing environments.eng
dc.identifier.citationLi, Fernanda; Barbosa, Daniela; Bashir, Sana; Moreira de Sá, Leandro; Yadró Garcia, Carlos A.; Rufino, José; Rosa-Fontana, Annelise; Verbinnen, Gilles; de Graaf, Dirk; de Smet, Lina; Taliadoros, Demetris; Webster, Matthew; Pinto, M. Alice; Henriques, Dora (2025). Genetic Diversity of Detoxification Genes in 18 Honey Bee Subspecies. VI International Conference of the Portuguese Society of Geneti. p.63
dc.identifier.urihttp://hdl.handle.net/10198/35743
dc.language.isoeng
dc.peerreviewedyes
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectApis mellifera
dc.titleGenetic Diversity of Detoxification Genes in 18 Honey Bee Subspecieseng
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferenceDate2025
oaire.citation.conferencePlaceOeiras, Portugal
oaire.citation.startPage63
oaire.citation.titleVI International Conference of the Portuguese Society of Geneti
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameLi
person.familyNameYadró Garcia
person.familyNameRufino
person.familyNamePinto
person.familyNameHenriques
person.givenNameFernanda
person.givenNameCarlos A.
person.givenNameJosé
person.givenNameM. Alice
person.givenNameDora
person.identifier.ciencia-idF115-6760-0EBB
person.identifier.ciencia-idF71F-B08E-EC39
person.identifier.ciencia-idC414-F47F-6323
person.identifier.ciencia-idF814-A1D0-8318
person.identifier.ciencia-id291F-986F-07DA
person.identifier.orcid0000-0003-0466-355X
person.identifier.orcid0000-0002-6916-3647
person.identifier.orcid0000-0002-1344-8264
person.identifier.orcid0000-0001-9663-8399
person.identifier.orcid0000-0001-7530-682X
person.identifier.scopus-author-id55947199100
person.identifier.scopus-author-id8085507800
person.identifier.scopus-author-id55761737300
relation.isAuthorOfPublication11ed7f07-945f-42e9-8950-eb6c59672e15
relation.isAuthorOfPublication59212a6c-fc6a-45fd-b37a-51e90926c9e3
relation.isAuthorOfPublication1e24d2ce-a354-442a-bef8-eebadd94b385
relation.isAuthorOfPublication0667fe04-7078-483d-9198-56d167b19bc5
relation.isAuthorOfPublicationd2abd09f-a90c-4cfb-9a60-7fc32f56184d
relation.isAuthorOfPublication.latestForDiscoveryd2abd09f-a90c-4cfb-9a60-7fc32f56184d

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
66.pdf
Tamanho:
465.72 KB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
1.75 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

CIMO - Resumos em Proceedings Não Indexados à WoS/Scopus