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A review on antifungal activity of mushroom (Basidiomycetes) extracts and isolated compounds

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dc.contributor.authorAlves, Maria José
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorDias, Joana F.
dc.contributor.authorTeixeira, Vânia
dc.contributor.authorMartins, Anabela
dc.contributor.authorPintado, Manuela
dc.date.accessioned2014-05-13T14:05:30Z
dc.date.available2014-05-13T14:05:30Z
dc.date.issued2013
dc.description.abstractThe present review reports the antifungal activity of mushroom extracts and isolated compounds including high (e.g. peptides and proteins) and low (e.g. sesquiterpenes and other terpenes, steroids, organic acids, acylcyclopentenediones and quinolines) molecular weight compounds. Most of the studies available on literature focused on screening of antifungal activity of mushroom extracts, rather than of isolated compounds. Data indicate that mushroom extracts are mainly tested against different Candida species, while mushroom compounds are mostly tested upon other fungi. Therefore, the potential of these compounds might be more useful in food industry than in clinics. Oudemansiella canarii and Agaricus bisporus methanolic extracts proved to be the most active mushroom extracts against Candida spp. Grifolin, isolated from Albatrellus dispansus, seemed to be the most active compound against phytopathogenic fungi. Further studies should be performed in order to better understand the mechanism of action of this and other antifungal compounds as well as safety issues.por
dc.description.sponsorshipFundação para a Ciência e a Tecnologia (FCT, Portugal) and COMPETE/QREN/EU for financial support to this work (research project PTDC/AGR-ALI/110062/2009; strategic projects PEst-OE/AGR/UI0690/2011 and PEst-OE/EQB/LA0016/2011). They also thank to CHTMAD – Hospital Center of Trás-os-Montes e Alto Douro and Siemens for all the support.por
dc.identifier.citationAlves, Maria José; Ferreira, Isabel C.F.R.; Dias, Joana F.; Teixeira, Vânia; Martins, Anabela; Pintado, Manuela (2013). A review on antifungal activity of mushroom (Basidiomycetes) extracts and isolated compounds. Current Topics in Medicinal Chemistry. ISSN 1568-0266. 13:21, p. 2648-2659por
dc.identifier.doi10.2174/15680266113136660191
dc.identifier.issn1568-0266
dc.identifier.urihttp://hdl.handle.net/10198/9505
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherBentham Sciencepor
dc.relationPEst-OE/AGR/ UI0690/2011
dc.relationPortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
dc.relationStrategic Project - LA 16 - 2011-2012
dc.subjectAntifungal activitypor
dc.subjectAntifungal proteinspor
dc.subjectBasidiomycetespor
dc.subjectGrifolinpor
dc.titleA review on antifungal activity of mushroom (Basidiomycetes) extracts and isolated compoundspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberPTDC/AGR-ALI/110062/2009
oaire.awardNumberPEst-OE/EQB/LA0016/2011
oaire.awardTitlePortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
oaire.awardTitleStrategic Project - LA 16 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FAGR-ALI%2F110062%2F2009/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0016%2F2011/PT
oaire.citation.endPage2659por
oaire.citation.startPage2648por
oaire.citation.titleCurrent Topics in Medicinal Chemistrypor
oaire.citation.volume13por
oaire.fundingStream5876-PPCDTI
oaire.fundingStream6817 - DCRRNI ID
person.familyNameAlves
person.familyNameFerreira
person.familyNameMartins
person.givenNameMaria José
person.givenNameIsabel C.F.R.
person.givenNameAnabela
person.identifier144781
person.identifier.ciencia-idD618-B3A9-D312
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id7B18-A810-6B93
person.identifier.orcid0000-0001-8506-4393
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0001-6218-4413
person.identifier.ridM-6624-2016
person.identifier.ridE-8500-2013
person.identifier.ridG-5488-2013
person.identifier.scopus-author-id16400584800
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id7203013518
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
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