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Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L.

2013Journal article Open access
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dc.contributor.authorBarros, Lillian
dc.contributor.authorPereira, Eliana
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorDueñas, Montserrat
dc.contributor.authorCarvalho, Ana Maria
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2014-01-27T11:59:27Z
dc.date.available2014-01-27T11:59:27Z
dc.date.issued2013
dc.description.abstractThe bioactive properties (antioxidant and antitumour activities, and hepatotoxicity) of the infusion and methanolic extracts of Chenopodium ambrosioides L., a plant commonly used in Portuguese folk medicine, were compared. The chemical composition in hydrophilic (sugars, organic acids and phenolic compounds) and lipophilic (fatty acids and tocopherols) fractions were determined. In general, the infusion revealed higher antioxidant activity, while the methanolic extract was the only one showing antitumour effects against colon, cervical and hepatocellular carcinoma cell lines. No toxicity in non-tumour cells was observed either for the infusion or the extract. The studied plant proved to be a good source of natural antioxidants and other bioactive compounds, which may have industrial use. As far as we know, this is the first detailed chemical characterization and bioactivity evaluation of C. ambrosioides methanolic extract and infusion.por
dc.description.sponsorshipFundação para a Ciência e a Tecnologia (FCT, Portugal) for financial support to CIMO (strategic project PEst-OE/AGR/UI0690/2011). R.C. Calhelha and L. Barros also thank to FCT, POPH-QREN and FSE for their grants (SFRH/BPD/ BPD/68344/2010 and SFRH/BPD/4609/2008, respectively). The GIP-USAL is financially supported by the Spanish Government through the Consolider-Ingenio 2010 Programme (FUN-C-FOOD, CSD2007-00063). M. Dueñas thanks to the Programa Ramón y Cajal for a contract.por
dc.identifier.citationBarros, Lillian; Pereira, Eliana; Calhelha, Ricardo C.; Dueñas, Montserrat; Carvalho, Ana Maria; Santos-Buelga, Celestino; Ferrreira, Isabel C.F.R. (2013). Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. Journal of Functional Foods. ISSN 1756-4646. 5:4, p. 1732–1740por
dc.identifier.issn1756-4646
dc.identifier.urihttp://hdl.handle.net/10198/9172
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationSFRH/BPD/ BPD/68344/2010
dc.relationStrategic Project - UI 690 - 2011-2012
dc.relation.publisherversionhttp://www.sciencedirect.com/science/journal/17564646por
dc.subjectChenopodium ambrosioides L.por
dc.subjectAntioxidant activitypor
dc.subjectAntitumour activitypor
dc.subjectChemical compoundspor
dc.titleBioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L.por
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.citation.endPage1740por
oaire.citation.startPage1732por
oaire.citation.titleJournal of Functional Foodspor
oaire.citation.volume5por
oaire.fundingStream6817 - DCRRNI ID
person.familyNameBarros
person.familyNamePereira
person.familyNameCalhelha
person.familyNameCarvalho
person.familyNameFerreira
person.givenNameLillian
person.givenNameEliana
person.givenNameRicardo C.
person.givenNameAna Maria
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifierID G-7399-2011
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idBE17-462D-9A75
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-idD31A-35AF-E2A9
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-2854-6745
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0001-5508-5935
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridQ-8017-2018
person.identifier.ridJ-2172-2014
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id55938912300
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id20336503900
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
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