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Bee propolis effect on protection of RBC’s membrane integrity

2009Conference object Open access
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dc.contributor.authorMoreira, Leandro
dc.contributor.authorRogão, Mónica
dc.contributor.authorPereira, Ana Paula
dc.contributor.authorMorais, Margarida
dc.contributor.authorCosta, Bruno
dc.contributor.authorDias, L.G.
dc.contributor.authorDias, Teresa
dc.contributor.authorEstevinho, Leticia M.
dc.date.accessioned2011-06-09T14:35:13Z
dc.date.available2011-06-09T14:35:13Z
dc.date.issued2009
dc.description.abstractPropolis is a resinous substance collected from plants by bees. The propolis composition depends on the surrounding vegetation, the season, and the area from which derive. This hive product usually contains a variety of chemical compounds such as polyphenols (flavonoids, phenolic acids and esters), steroids, and amino acids. The hereditary spherocytosis (HS) is a congenital hemolytic anemia, with origin in the modification of membrane proteins of erythrocytes, which leads to increased susceptibility to hemolysis and a decrease of the cell over-life. The HS is the most common red blood cell (RBC) membrane disorder in European Caucasians, with a prevalence of roughly 200-300 per 106, and to Japanese population 5.7-20.3 per 106. The aim of the present work was to determine if propolis extracts could affected the red cell membrane integrity and comparing the effect of two propolis extracts from different regions (Bornes - Trás-os-Montes; Fundão - Beira Interior). In this work, two adults were studied, one with the syndrome HS splenectomized and one healthy used as control. Diagnosis of HS was made by clinical features, identification of spherocytes on peripheral blood smears and abnormal osmotic fragility. The results show that the two propolis extracts affected the erythrocyte membrane fragility in both individuals (control and patient with HS).por
dc.identifier.citationMoreira, Leandro; Pereira, Ana Paula; Morais, Margarida; Costa, Bruno; Dias, Luis; Dias, Teresa; Estevinho, Leticia M. (2009). Bee propolis effect on protection of rbc’s membrane integrity. In Microbiotec’09. Albufeirapor
dc.identifier.urihttp://hdl.handle.net/10198/5098
dc.language.isoengpor
dc.peerreviewedyespor
dc.titleBee propolis effect on protection of RBC’s membrane integritypor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceAlbufeira, Algarvepor
oaire.citation.titleMicrobiotec’09por
person.familyNamePereira
person.familyNameGuimarães Dias
person.familyNameDias
person.familyNameMiranda Fernandes Estevinho
person.givenNameAna Paula
person.givenNameLuís Avelino
person.givenNameTeresa
person.givenNameMaria Leticia
person.identifier142703
person.identifier.ciencia-id1413-70AA-CDF6
person.identifier.ciencia-id2F11-9092-FAAF
person.identifier.ciencia-idBA14-09D6-A406
person.identifier.orcid0000-0003-1489-5207
person.identifier.orcid0000-0002-1210-4259
person.identifier.orcid0000-0002-9419-9561
person.identifier.orcid0000-0002-9249-1948
person.identifier.scopus-author-id54401473200
person.identifier.scopus-author-id23569169900
person.identifier.scopus-author-id56830642600
person.identifier.scopus-author-id6506577664
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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relation.isAuthorOfPublication.latestForDiscovery4a1d5ba2-1854-4ca5-89a4-73f35e964df9

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