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Influence of mobile phase composition on the preparative separation of profens by chiral liquid chromatography

dc.contributor.authorRibeiro, António E.
dc.contributor.authorPais, Luís S.
dc.contributor.authorRodrigues, Alírio
dc.date.accessioned2011-12-02T15:19:26Z
dc.date.available2011-12-02T15:19:26Z
dc.date.issued2005
dc.description.abstractThe chirality of drugs is an important issue for the pharmaceutical industry, since the different enantiomers of a racemic drug may have distinct pharmacological activities, pharmacokinetic and pharmacodynamic effects. Because of its chiral selectivity, human body reacts with a racemic drug differently, and metabolise each enantiomer on separate pathways producing different pharmacological activity. Thus, one isomer may produce the desired therapeutic activities, while the other may be inactive or even, in worst cases, produce unwanted effects.por
dc.identifier.citationRibeiro, A.E.; Pais, L.S.; Rodrigues, A. (2005). Influence of mobile phase composition on the preparative separation of profens by chiral liquid chromatography. In in ChemPor/05 9th Interantional Engineering Conference. Coimbra.por
dc.identifier.urihttp://hdl.handle.net/10198/6366
dc.language.isoengpor
dc.peerreviewedyespor
dc.titleInfluence of mobile phase composition on the preparative separation of profens by chiral liquid chromatographypor
dc.typeconference poster
dspace.entity.typePublication
person.familyNameRibeiro
person.familyNamePais
person.givenNameAntónio E.
person.givenNameLuís S.
person.identifier.ciencia-id3211-D5B0-870D
person.identifier.ciencia-id421E-0CCD-A84F
person.identifier.orcid0000-0003-4569-7887
person.identifier.orcid0000-0002-3000-2862
person.identifier.scopus-author-id23390701300
person.identifier.scopus-author-id6603930478
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication52666376-f100-4407-87ef-dc5df3613761
relation.isAuthorOfPublicationc6d25534-8487-45b1-90af-d350f4e3ac55
relation.isAuthorOfPublication.latestForDiscoveryc6d25534-8487-45b1-90af-d350f4e3ac55

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