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Agaricus blazei Murril - a potential ingredient for nutraceutical outcomes

2018Conference object Open access
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dc.contributor.authorTaofiq, Oludemi
dc.contributor.authorRodrigues, Francisca
dc.contributor.authorBarros, Lillian
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorGonzález-Paramás, Ana María
dc.contributor.authorBarreiro, M.F.
dc.contributor.authorOliveira, Beatriz
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-11-12T11:24:22Z
dc.date.available2018-11-12T11:24:22Z
dc.date.issued2018
dc.description.abstractThe concept of bio-economy has emerged to overcome some sustainability challenges, and this involves conversion of agricultural residues and waste streams into high value-added products that can be utilized as ingredients for several bio-based industrial processes, delivering both economic growth, scientific interest and a better environment. The present work was carried out to re-utilize discarded Agaricus blazei Murill. Its nutritional composition was evaluated and ethanolic extracts were prepared by Soxhlet extraction to be further evaluated for their anti-inflammatory, anti-tyrosinase and cytotoxic properties against different tumor cell lines (SRB assay). MTT and LDH assays were also used to determine cell viability and cell death respectively in Caco-2 and HT29 cells lines. Essential nutrients such as carbohydrates, proteins and fat, were found; twenty fatty acids were detected, sugars (mannitol and trehalose), α-tocopherol and oxalic acid were also present. The extracts, up to 100 μg/mL, were able to maintain viability of Caco-2 and HT29 cells. The extracts also presented anti-tyrosinase activity (EC50 1.33±0.02 mg/mL) and with no toxicity in tumor cells. The results obtained suggested that the extracts obtained from Agaricus blazei Murill residues can be utilized as an inexpensive and sustainable source of nutraceutical and functional food ingredients.pt_PT
dc.description.sponsorshipFCT for financial support to CIMO (UID/AGR/00690/2013); European Agricultural Fund for Rural Development (EAFRD), through the Rural Development Program (PDR2020), within the scope of Project MicoCoating (PDR2020-101-031472). This work also received financial support from the European Union (FEDER funds through COMPETE), under the Partnership Agreement PT2020, and National Funds (FCT, Foundation for Science and Technology) through project LAQV/UID/QUI/50006/2013 and NORTE-07-0124-FEDER-000069 – Food Science.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTaofiq, Oludemi; Rodrigues, Francisca; Barros, Lillian; Calhelha, Ricardo C.; González-Paramás, Ana M.; Barreiro, M.F.; Oliveira, M.B.P.P.; Ferreira, Isabel C.F.R. (2018). Agaricus blazei Murril - a potential ingredient for nutraceutical outcomes. In XIV Encontro de Química dos Alimentos. Viana do Castelo. ISBN 978-989-98936-9-6pt_PT
dc.identifier.isbn978-989-98936-9-6
dc.identifier.urihttp://hdl.handle.net/10198/18174
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAgaricus blazei Murril
dc.subjectPropriedades anti-inflamatórias
dc.titleAgaricus blazei Murril - a potential ingredient for nutraceutical outcomespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F50006%2F2013/PT
oaire.citation.conferencePlaceViana do Castelo, Portugalpt_PT
oaire.citation.title14º Encontro de Química dos Alimentospt_PT
oaire.fundingStream5876
oaire.fundingStream5876
person.familyNameBarros
person.familyNameCalhelha
person.familyNameBarreiro
person.familyNameFerreira
person.givenNameLillian
person.givenNameRicardo C.
person.givenNameFilomena
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-id3418-47D5-5746
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0002-6844-333X
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridJ-2172-2014
person.identifier.ridL-9802-2014
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id57188719717
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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