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Tocopherols in Ginkgo biloba L.: A comparative study between infusion and dietary suplements

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dc.contributor.authorPereira, Eliana
dc.contributor.authorBarros, Lillian
dc.contributor.authorBarreira, João C.M.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2014-05-12T13:31:57Z
dc.date.available2014-05-12T13:31:57Z
dc.date.issued2013
dc.description.abstractThe concentrated extracts of Ginkgo biloba leaves have been marketed in Western countries as herbal medicines, which due to their bioactive compounds contribute for the improvement of cerebral blood flow and memory [1]. One of those compounds is α-tocopherol, which intervenes in the reduction of symptoms associated with oxidative stress in neurodegenerative disorders, particularly Alzheimer's disease. α-Tocopherol, an isoform of the lipid soluble vitamin E, is well-known as an antioxidant, and has been widely investigated as a potential prophylactic dietary supplement in cardiovascular diseases [2,3]. The objective of this study was to evaluate the amount and profile of tocopherols in some dietary supplements: pills based on G. biloba leaves standardized extract with 24% glycosides and 6% terpenes (P1, 40 mg/pill; P2, 60 mg/pill; and P3, 100 mg/pill); oral solution (OS- 40 mg of G. bilobo standardized extract/mL); and compare them with the infusion of G. bi/obo wild leaves (LI). Tocopherols were identified and quantified by high performance liquid chromatography coupled to a fluorescence detector (H PLCfluorescence). All the vitamers α-, β-, γ- and δ-tocopherol were found in the infusion, but not in dietary supplements. Furthermore, the infusion gave the highest amount of total tocopherols (126.23 mg/100 g dw) and of each individual vitamer; α-tocopherol was, by far, the most abundant tocopherol in that sample (124.88 mg/100 g dw). This study showed that wild G. bi/obo infusion supplies a much higher amount of tocopherols than dietary supplements based on the same plant. Moreover, its consumption could be beneficial due to the capacity of α-tocopherol to eliminate reactive oxygen species, inhibit lipid peroxidation, and attenuate inflammatory reactions.por
dc.description.sponsorshipFCT for financial support to CIMO (PEst-OE/AGR/UI0690/2011) and L. Barros (Compromisso para a Ciencia 2008).por
dc.identifier.citationPereira, Eliana; Barros, Lillian; Barreira, João C.M.; Ferreira, Isabel C.F.R. (2013). Tocopherols in Ginkgo biloba L.: A comparative study between infusion and dietary supplements. In 8º Encontro Nacional de Cromatografia. Covilhãpor
dc.identifier.urihttp://hdl.handle.net/10198/9489
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationStrategic Project - UI 690 - 2011-2012
dc.titleTocopherols in Ginkgo biloba L.: A comparative study between infusion and dietary suplementspor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.citation.conferencePlaceCovilhã, Portugalpor
oaire.citation.title8º Encontro Nacional de Cromatografiapor
oaire.fundingStream6817 - DCRRNI ID
person.familyNamePereira
person.familyNameBarros
person.familyNameBarreira
person.familyNameFerreira
person.givenNameEliana
person.givenNameLillian
person.givenNameJoão
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-idBE17-462D-9A75
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-2854-6745
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-1233-0990
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridQ-8017-2018
person.identifier.ridJ-3600-2013
person.identifier.ridD-8269-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id55938912300
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id54895546900
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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