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Chemical and bioactive characterization of spanish and belgian apple pomace for its potential use as a novel dermocosmetic formulation

2021Artigo científico Acesso aberto
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dc.contributor.authorAlvarez Arraibi, Ana
dc.contributor.authorLiberal, Ângela
dc.contributor.authorDias, Maria Inês
dc.contributor.authorAlves, Maria José
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.contributor.authorBarreira, João C.M.
dc.date.accessioned2021-10-15T10:39:00Z
dc.date.available2021-10-15T10:39:00Z
dc.date.issued2021
dc.description.abstractCurrently, there is a general trend towards reutilizing industrial by-products that would otherwise be discarded or considered as waste, aiming to explore them as alternative sources of valuable compounds. The apple pomace remaining from cider and apple juice industries represents a high-potential source of bioactive compounds with putative application in food or pharmaceuticalrelated products. Accordingly, the work reported herein was conducted to characterize the phenolic compounds in apple pomace from Belgium and Spain, as well as to evaluate its chemical composition and particular types of bioactivity. As a proof of concept, a new hydrogel was prepared, incorporated with the bioactive compounds and pectin extracted from apple pomace, aiming to obtain the most organic formulation possible. Independently of the extracting agent, it became evident that using lyophilization as the drying step is a better choice than thermal processes as it yielded a richer phenolic profile (fifteen individual compounds), with 5-O-caffeoylquinic acid as the major compound (66 to 114 mg/100 g dw) in Belgian samples. In general, the hydroethanolic extracts showed the strongest antioxidant and antimicrobial (particularly against Propionibacterium acnes: MIC = 2.5 mg/mL) activities. This result, together with the lipid nature of human skin, led it to be chosen as the extract type to be incorporated in the hydrogel. In general, apple pomace stood out as a valuable source of bioactive compounds, especially polyphenols and pectin, with good potential to be incorporated in dermal formulations.pt_PT
dc.description.sponsorshipThis research was funded by Foundation for Science and Technology (FCT, Portugal) through national funds to CIMO (UIDB/00690/2020), the institutional scientific employment program contract for L. Barros and M.I. Dias and through the individual scientific employment program contract for J. Barreira. Research was also funded by the FEDER Interreg España–Portugal program through the project TRANSCoLAB 0612_TRANS_CO_LAB_2_P and by the ERDF through the Regional Operational Program North 2020, within the scope of project Mobilizador Norte-01-0247- FEDER-024479: ValorNatural® and Project GreenHealth-Norte-01-0145-FEDER-000042.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAlvarez Arraibi, Ana, Liberal, Ângela; Dias, Maria Inês; Alves, Maria José; Ferreira, Isabel C.F.R.; Barros, Lillian; Barreira, João C.M. (2021). Chemical and bioactive characterization of spanish and belgian apple pomace for its potential use as a novel dermocosmetic formulation. Foods. ISSN 2304-8158. 10:8, p. 1-14pt_PT
dc.identifier.doi10.3390/foods10081949pt_PT
dc.identifier.issn2304-8158
dc.identifier.urihttp://hdl.handle.net/10198/24039
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationMountain Research Center
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectApple pomacept_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectCosmeceuticalspt_PT
dc.subjectAnti-acne activitypt_PT
dc.subjectNatural hydrogel formulationspt_PT
dc.titleChemical and bioactive characterization of spanish and belgian apple pomace for its potential use as a novel dermocosmetic formulationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.citation.issue8pt_PT
oaire.citation.startPage1949pt_PT
oaire.citation.titleFoodspt_PT
oaire.citation.volume10pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameLiberal
person.familyNameDias
person.familyNameAlves
person.familyNameFerreira
person.familyNameBarros
person.familyNameBarreira
person.givenNameÂngela
person.givenNameMaria Inês
person.givenNameMaria José
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.givenNameJoão C.M.
person.identifier144781
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person.identifier.orcid0000-0003-4910-4882
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person.identifier.ridM-8242-2013
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person.identifier.scopus-author-id54388787000
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person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id54895546900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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