Publication
Evaluation of Arenaria montana L. hydroethanolic extract as a chemopreventive food ingredient: A case study focusing a dairy product (yogurt)
| dc.contributor.author | Oliveira, Franciely dos Santos de | |
| dc.contributor.author | Ribeiro, Andreia | |
| dc.contributor.author | Barros, Lillian | |
| dc.contributor.author | Calhelha, Ricardo C. | |
| dc.contributor.author | Barreira, João C.M. | |
| dc.contributor.author | Demczuk Junior, Bogdan | |
| dc.contributor.author | Abreu, Rui M.V. | |
| dc.contributor.author | Barreiro, M.F. | |
| dc.contributor.author | Ferreira, Isabel C.F.R. | |
| dc.date.accessioned | 2018-01-25T10:00:00Z | |
| dc.date.accessioned | 2018-01-29T10:39:41Z | |
| dc.date.available | 2018-01-25T10:00:00Z | |
| dc.date.available | 2018-01-29T10:39:41Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Natural ingredients are valuable options to be exploited in the design of innovative food formulations with health benefits. Therefore, it was evaluated the potential use of Arenaria montana L. hydroethanolic extract (rich in apigenin derivatives) as a chemopreventive agent in functional foods. Apigenin is recognized as inhibiting VEGFR-2, which is the key receptor involved in angiogenesis. The obtained extract was also able to inhibit the VEGFR-2 phosphorylation through an enzymatic assay (IC 50 = ~63 µg/mL). Thereafter, free and microencapsulated forms were incorporated in yogurt. The obtained products maintained the nutritional value along the tested 3 days of storage, as also free sugars and fatty acids profiles, in comparison with the control samples. Nevertheless, the VEGFR-2 phosphorylation inhibition was not exhibited as intended. Even this behavior for the microencapsulated forms can be attributed to the protecting effect of the alginate matrix, further studies are required in order to better understand the shown performance. | pt_PT |
| dc.description.sponsorship | The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER for CIMO (UID/AGR/00690/2013) financial support. To POCI-01-0145-FEDER-006984 (LA LSRE-LCM) funded by ERDF through POCI-COMPETE2020 and FCT. To NORTE-01-0145-FEDER-000006, funded by NORTE 2020, under PT2020 through ERDF. L. Barros, R.C. Calhelha and J.C.M. Barreira acknowledge the FCT for their post-doctoral grants (SFRH/BPD/107855/2015, SFRH/BPD/68344/2010 and SFRH/BPD/72802/2010, respectively). The authors also thank Ana Maria Carvalho for providing Arenaria montana L. samples. | |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Oliveira, Franciely S.; Ribeiro, Andreia; Barros, Lillian; Calhelha, Ricardo C.; Barreira, João C.M.; Junior, Bogdan D.; Abreu, Rui M.V.; Barreiro, M.F.; Ferreira, Isabel C.F.R. (2017). Evaluation of Arenaria montana L. hydroethanolic extract as a chemopreventive food ingredient: A case study focusing a dairy product (yogurt). Journal of Functional Foods. ISSN 1756-4646. 38, Part A, p. 214-220 | |
| dc.identifier.doi | 10.1016/j.jff.2017.09.027 | pt_PT |
| dc.identifier.issn | 1756-4646 | |
| dc.identifier.uri | http://hdl.handle.net/10198/15078 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | pt_PT |
| dc.relation | Providing industry and consumers with new alternative sources of natural additives from plant origin in the classes of preservatives and colouring agents: extraction, purification, stabilization and product development | |
| dc.relation | BIOACTIVE PROPERTIES & CYTOPROTECTIVE POTENTIAL OF NATURAL EXTRACTS/INDIVIDUAL COMPOUNDS: APPLICATION OF SINGLE CELL GEL ELECTROPHORESIS AND OTHER BIOCHEMICAL, CHEMICAL AND ELECTROCHEMICAL ASSAYS | |
| dc.title | Evaluation of Arenaria montana L. hydroethanolic extract as a chemopreventive food ingredient: A case study focusing a dairy product (yogurt) | en_EN |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Providing industry and consumers with new alternative sources of natural additives from plant origin in the classes of preservatives and colouring agents: extraction, purification, stabilization and product development | |
| oaire.awardTitle | BIOACTIVE PROPERTIES & CYTOPROTECTIVE POTENTIAL OF NATURAL EXTRACTS/INDIVIDUAL COMPOUNDS: APPLICATION OF SINGLE CELL GEL ELECTROPHORESIS AND OTHER BIOCHEMICAL, CHEMICAL AND ELECTROCHEMICAL ASSAYS | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F107855%2F2015/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F68344%2F2010/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F72802%2F2010/PT | |
| oaire.fundingStream | 5876 | |
| oaire.fundingStream | SFRH | |
| person.familyName | Barros | |
| person.familyName | Calhelha | |
| person.familyName | Barreira | |
| person.familyName | Abreu | |
| person.familyName | Barreiro | |
| person.familyName | Ferreira | |
| person.givenName | Lillian | |
| person.givenName | Ricardo C. | |
| person.givenName | João C.M. | |
| person.givenName | Rui M.V. | |
| person.givenName | Filomena | |
| person.givenName | Isabel C.F.R. | |
| person.identifier | 469085 | |
| person.identifier | 144781 | |
| person.identifier.ciencia-id | 9616-35CB-D001 | |
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| person.identifier.orcid | 0000-0002-6844-333X | |
| person.identifier.orcid | 0000-0003-4910-4882 | |
| person.identifier.rid | J-3600-2013 | |
| person.identifier.rid | J-2172-2014 | |
| person.identifier.rid | D-8269-2013 | |
| person.identifier.rid | L-9802-2014 | |
| person.identifier.rid | E-8500-2013 | |
| person.identifier.scopus-author-id | 35236343600 | |
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| person.identifier.scopus-author-id | 36868826600 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | en_EN |
| rcaap.type | article | pt_PT |
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