Publication
Tandem palladium-catalyzed borylation and suzuki coupling (BSC) to thienocarbazole precursors
| dc.contributor.author | Ferreira, Isabel C.F.R. | |
| dc.contributor.author | Queiroz, Maria João R.P. | |
| dc.contributor.author | Kirsch, Gilbert | |
| dc.date.accessioned | 2008-09-12T13:08:20Z | |
| dc.date.available | 2008-09-12T13:08:20Z | |
| dc.date.issued | 2003 | |
| dc.description.abstract | Substituted 2-methyl-2'-nitro diaryl compounds in the benzo[b]thiophene series were prepared by palladium-catalyzed, two-step, one-pot borylation/Suzuki coupling (BSC) reaction in good to high yields. The borylation reaction was performed on methylated 6-bromobenzo[b]thiophenes using pinacolborane and was followed by in situ Suzuki coupling with substituted (CF3, OMe) 2-bromonitrobenzenes. The compounds obtained were cyclized to the corresponding ring A substituted thienocarbazoles which can have biological activity or/and be used as biomarkers due to their fluorescence properties and possible DNA intercalation. | en |
| dc.identifier.citation | Ferreira, Isabel C.F.R.; Queiroz, Maria João R.P.; Kirsch, Gilbert (2003). Tandem palladium-catalyzed borylation and suzuki coupling (BSC) to thienocarbazole precursors. Tetrahedron Letters. ISSN 0040-4039. 44:23 (2003) p. 4327-4329 | en |
| dc.identifier.doi | 10.1016/S0040-4039(03)00952-3 | |
| dc.identifier.issn | 0040-4039 | |
| dc.identifier.uri | http://hdl.handle.net/10198/819 | |
| dc.language.iso | eng | en |
| dc.publisher | Elsevier | en |
| dc.subject | Palladium | en |
| dc.subject | Borylation | en |
| dc.subject | Suzuki coupling | en |
| dc.subject | 2-methyl-2'-nitro biaryls | en |
| dc.subject | Benzo[b]thiophenes | en |
| dc.title | Tandem palladium-catalyzed borylation and suzuki coupling (BSC) to thienocarbazole precursors | en |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| person.familyName | Ferreira | |
| person.givenName | Isabel C.F.R. | |
| person.identifier | 144781 | |
| person.identifier.ciencia-id | 9418-CF95-9919 | |
| person.identifier.orcid | 0000-0003-4910-4882 | |
| person.identifier.rid | E-8500-2013 | |
| person.identifier.scopus-author-id | 36868826600 | |
| rcaap.rights | openAccess | |
| rcaap.type | article | en |
| relation.isAuthorOfPublication | bd0d1537-2e03-41fb-b27a-140af9c35db8 | |
| relation.isAuthorOfPublication.latestForDiscovery | bd0d1537-2e03-41fb-b27a-140af9c35db8 |