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Blood flow in a bifurcation and confluence microchannel: effect of the cell-free layer in velocity profiles

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dc.contributor.authorPinho, Diana
dc.contributor.authorBento, David
dc.contributor.authorRodrigues, Raquel Oliveira
dc.contributor.authorFernandes, Carla S.
dc.contributor.authorGarcia, Valdemar
dc.contributor.authorLima, Rui A.
dc.date.accessioned2014-07-31T10:19:14Z
dc.date.available2014-07-31T10:19:14Z
dc.date.issued2014
dc.description.abstractA few detailed studies have been performed in complex in vitro microvascular networks composed by bifurcations and confluences. The main purpose of the present work is to numerically simulate the flow of two distinct fluids through bifurcation and confluence geometries, i. e red blood cells (RBCs)suspended in Dextran40 with about 14% of heamatocrit and pure water. The simulations of pure water and RBCs flows were performed resorting to the commercial finite volume software package FLUENT. A well known hemodynamic phenomenon, known as Fahraeus-Lindqvist effect, observed in both in vivo and in vitro studies, results in the formation of a marginal cell-free layer (CFL) at regions adjacent to the wall. Recently, studies have shown that the formation of the CFL is affected by the geometry of the microchannel and for the case of the confluences a CFL tend to appear in the middle of the microchannel after the apex of the confluence. By using the CFL experimental data, the main objective of this work is to implement a CFL in the numerical simulations in order to obtain a better understanding of the effect of this layer on the velocity profiles.por
dc.identifier.citationPinho, Diana; Bento, David; Rodrigues, Raquel; Fernand es, Carla S.; Garcia, Valdemar; Lima, R. (2014). Blood flow in a bifurcation and confluence microchannel : effect of the cell-free layer in velocity profiles. In 7th World Congress of Biomechanics. Bostonpor
dc.identifier.urihttp://hdl.handle.net/10198/9990
dc.language.isoporpor
dc.peerreviewedyespor
dc.relationANEURYSM - Hemodynamic Study in Cerebral Aneurysms
dc.relationMicroBloodSystems - Blood rheology and blood cell migration in microfluidic systems
dc.subjectVelocity profilespor
dc.subjectCell-free layerpor
dc.titleBlood flow in a bifurcation and confluence microchannel: effect of the cell-free layer in velocity profilespor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleANEURYSM - Hemodynamic Study in Cerebral Aneurysms
oaire.awardTitleMicroBloodSystems - Blood rheology and blood cell migration in microfluidic systems
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FEME-MFE%2F099109%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/EXPL%2FEMS-SIS%2F2215%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-BEB%2F105650%2F2008/PT
oaire.citation.conferencePlaceBostonpor
oaire.citation.title7th World Congress of Biomechanicspor
oaire.fundingStream5876-PPCDTI
oaire.fundingStream5876-PPCDTI
oaire.fundingStream5876-PPCDTI
person.familyNamePinho
person.familyNameFernandes
person.familyNameGarcia
person.familyNameLima
person.givenNameDiana
person.givenNameCarla S.
person.givenNameValdemar
person.givenNameRui A.
person.identifier.ciencia-id5214-ED0C-35E8
person.identifier.ciencia-idF319-3D67-9DB7
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.orcid0000-0002-3884-6496
person.identifier.orcid0000-0002-3138-7493
person.identifier.orcid0000-0002-3941-2438
person.identifier.orcid0000-0003-3428-637X
person.identifier.ridA-4269-2015
person.identifier.ridH-5157-2016
person.identifier.scopus-author-id8253740700
person.identifier.scopus-author-id18437397800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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