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Natural β-chitin-protein complex film obtained from waste razor shells for transdermal capsaicin carrier

2020Journal article Open access
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dc.contributor.authorAylanc, Volkan
dc.contributor.authorErtosun, Seymanur
dc.contributor.authorAkyuz, Lalehan
dc.contributor.authorKoc Bilican, Behlul
dc.contributor.authorGokdag, Semih
dc.contributor.authorBilican, Ismail
dc.contributor.authorCakmak, Yavuz Selim
dc.contributor.authorYilmaz, Bahar Akyuz
dc.contributor.authorKaya, Murat
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2020-06-22T10:18:11Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2020-06-22T10:18:11Z
dc.date.issued2020
dc.description.abstractIn the literature, the produced β-chitin samples are in powder or flake forms but there is no natural β-chitin based film. Also, the commercially available transdermal patches are produced from synthetic polymers. In this regard,we produced natural β-chitin-protein complex (CPC) film fromthewaste shells of Ensis spp. The obtained natural filmwas characterized by FTIR, TGA and SEM. Additionally, swelling, thickness, contact angle and antioxidant tests were done to learn more about the films. After production and characterization of the film, capsaicin, which is commonly used for pain reliefwas loaded into the film. The loading capacitywas recorded as 5.79%. The kineticmodelswere studied in three different pH, then the resultswere fittedwith Higuchimodelwith high correlation at pH 7.4. After considering all the obtained results, the capsaicin loaded CPC film may be an alternative candidate for transdermal patch instead of the synthetic ones.
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationAylanc, Volkan; Ertosun, Seymanur; Akyuz, Lalehan; Koc Bilican, Behlul; Gokdag, Semih; Bilican, Ismail; Cakmak, Yavuz Selim; Yilmaz, Bahar Akyuz; Kaya, Murat (2020). Natural β-chitin-protein complex film obtained from waste razor shells for transdermal capsaicin carrier. International Journal of Biological Macromolecules. ISSN 0141-8130. 155, p. 508-515en_EN
dc.identifier.doi10.1016/j.ijbiomac.2020.03.232en_EN
dc.identifier.issn0141-8130
dc.identifier.urihttp://hdl.handle.net/10198/20282
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.subjectBio-wasteen_EN
dc.subjectBiodegradable filmen_EN
dc.subjectCapsaicinen_EN
dc.subjectTransdermal patchen_EN
dc.subjectβ-chitinen_EN
dc.titleNatural β-chitin-protein complex film obtained from waste razor shells for transdermal capsaicin carrieren_EN
dc.typejournal article
dspace.entity.typePublication
person.familyNameAylanc
person.familyNameErtosun
person.givenNameVolkan
person.givenNameSeymanur
person.identifier.ciencia-idFB10-056C-9A56
person.identifier.ciencia-id1A15-6D5C-D55E
person.identifier.orcid0000-0003-4060-766X
person.identifier.orcid0000-0002-9146-4040
person.identifier.scopus-author-id57189037561
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublication879e727d-327b-480c-9e44-5cd58c6a987f
relation.isAuthorOfPublication12f2b6b8-d96c-4b77-9d42-4b3938c9f4b7
relation.isAuthorOfPublication.latestForDiscovery879e727d-327b-480c-9e44-5cd58c6a987f

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