Repository logo
 
Publication

A comparative study between antioxidant properties of Ginkgo biloba L. infusion and dietary supplements

2013Conference object Open access
Simple item page
dc.contributor.authorPereira, Eliana
dc.contributor.authorBarros, Lillian
dc.contributor.authorBatista, Eugénia
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2013-09-09T10:27:15Z
dc.date.available2013-09-09T10:27:15Z
dc.date.issued2013
dc.description.abstractThe medical interest in western Ginkgo bilobaL. has increased since the 1980s, due to its potent action on the cerebral vascular activity and, in particular, for Alzheimer's disease. A variety of mechanisms of neuronal degeneration in Alzheimer's disease has been proposed, which includes formation of free radicals and oxidative stress [1 ,2]. Regarding the described correlation between antioxidants and Alzheimer's disease, and considering the use of G. biloga in the mentioned pathology, in the present study, the antioxidant activity of different dietary supplements (pills based on G. biloba leaves standardized extract with 24% glycosides and 6% terpenes- P1, P2 and P3) was evaluated and compared to the leaves infusion (LI).The samples from dietary supplements were prepared as indicated in the label by dissolving each pill in distilled water; P1 , P2 and P3 correspond to pills with 40, 60 and 100 mg of G. biloba standardized extract, respectively).Several dilutions of all the prepared solutions were used in the antioxidant activity assays, which include evaluation of free radicals scavenging activity, reducing power and lipid peroxidation inhibition. Contents in phenolics and flavonoids were also obtained by calorimetric assays. In generai,P2 and P3 samples revealed the highest antioxidant activity; P2 showed higher free radicals scavenging activity (EC50=70 μg/ml) and reducing power (EC50=60 μQ/mL), while P3 gave higher lipid peroxidation inhibition in a β-carotene-linoleate model system (EC50=220 μg/ml) and in brain homogenates (EC50=20 μg/ml).The mentioned samples also gave the highest amount of phenolics and flavonoids. Overall, dietary supplements based on standardized extracts of G. biloba leaves provide higher antioxidant properties than leaves infusion. Furthermore, the increase of the mass extract in the pills also contributed to increase the antioxidant potential, since P1 (with the lowest amount of extract- 40 mg) presented the lowest properties. This study showed that bioactive compounds present in the dietary supplements are different than the ones present in leaves infusion, and should be determined.por
dc.description.sponsorshipFCT for financial support to CIMO (strategic project PEstOE/ AGR/UI0690/2011). L. Barros also thanks to FCT, POPH-QREN and FSE for her grant (SFRH/BPD/4609/2008).por
dc.identifier.citationPereira, Eliana; Barros, Lillian; Batista, Eugénia; Ferreira, Isabel C.F.R. (2013). A comparative study between antioxidant properties of Ginkgo biloba L. infusion and dietary supplements. In 1st Symposium on Medicinal Chemistry. Bragapor
dc.identifier.urihttp://hdl.handle.net/10198/8667
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationSFRH/BPD/4609/2008
dc.relationStrategic Project - UI 690 - 2011-2012
dc.titleA comparative study between antioxidant properties of Ginkgo biloba L. infusion and dietary supplementspor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.citation.conferencePlaceBraga, Portugalpor
oaire.citation.title1st Symposium on Medicinal Chemistry of University of Minhopor
oaire.fundingStream6817 - DCRRNI ID
person.familyNamePereira
person.familyNameBarros
person.familyNameFerreira
person.givenNameEliana
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-idBE17-462D-9A75
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-2854-6745
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridQ-8017-2018
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id55938912300
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublicationdda60cdc-0a2a-4c10-863e-eaef1e6f1fb9
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscoverydda60cdc-0a2a-4c10-863e-eaef1e6f1fb9
relation.isProjectOfPublicationc59f09d4-9931-4f2e-babb-ef8bed998be7
relation.isProjectOfPublication.latestForDiscoveryc59f09d4-9931-4f2e-babb-ef8bed998be7

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Poster Nac. 133.pdf
Size:
500.74 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Resumos em Proceedings Não Indexados à WoS/Scopus