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Application of spray-coagulation method to microencapsulate catechin having in view cosmetic, pharmaceutical or nutraceutical areas

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dc.contributor.authorViegas, Joana
dc.contributor.authorBarros, Lillian
dc.contributor.authorFernandes, Isabel P.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarreiro, M.F.
dc.date.accessioned2013-09-10T09:20:22Z
dc.date.available2013-09-10T09:20:22Z
dc.date.issued2013
dc.description.abstractCatechin is a polyphenolic compound of the flavonoid family and a product of the secondary metabolism of various plants [1 ]. Antioxidant and chelating properties are attributed to catechin, as well as to other flavonoids, due to their aromatic hydroxyl groups. The presence of these bioactive components in diets rich in vegetables offers a protective effect in human health, including prevention of cardiovascular disorders and certain cancers, and in the ageing process itself. When ingested, catechin undergoes a process of metabolism that changes its structure affecting the antioxidant properties [2]. Microencapsulation can be used to overcome this problem offering protection by means of a cover material and enabling its controlled release over time or selectively to an intended target [3]. In this study catechin was microencapsulated in an alginate matrix by using a spray-coagulation technique. Briefly, a sodium alginate solution (4%, w/v) containing catechin was prepared under stirring at ambient temperature by using a ratio catechin:alginate of 25:400 (w/w). The solution was atomized in a Nisco Var J30 unit and microspheres consolidated upon contact with a solution of CaCI2 (4%, w/v), recovered by decantation and washed with deionized water. In order to control the process, microspheres formation was followed by optical microscopy (OM), and catechin loss evaluated after consolidation/washing steps. In conclusion, alginate-based microspheres loaded with catechin were efficiently produced. The obtained microspheres have a medium particle size comprised between 73 and 341 1-Jm and encapsulation efficiency was estimated as 87%. Overall, catechin was microencapsulated with success, and can be incorporated in different formulations in order to apply its antioxidant properties in cosmetic, pharmaceutical or nutraceutical areas. The work will proceed by evaluating the protective effect of the used microencapsulation process on catechin antioxidant properties.por
dc.description.sponsorshipFCT for financial support to CIMO (strategic project PEstOE/ AGR/UI0690/2011) and to LSRE (strategic project PEst-C/EQB/LA0020/2011 }. L. Barros also thanks to FCT, POPH-QREN and FSE for her grant (SFRH/BPD/4609/2008)por
dc.identifier.citationViegas, Joana; Barros, Lillian; Fernandes, Isabel; Ferreira, Isabel C.F.R.; Barreiro, Filomena (2013). Application of spray-coagulation method to microencapsulate catechin having in view cosmetic, pharmaceutical or nutraceutical areas. In 1st Symposium on Medicinal Chemistry. Bragapor
dc.identifier.urihttp://hdl.handle.net/10198/8701
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationPEstOE/AGR/UI0690/2011
dc.relationStrategic Project - LA 20 - 2011-2012
dc.titleApplication of spray-coagulation method to microencapsulate catechin having in view cosmetic, pharmaceutical or nutraceutical areaspor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleStrategic Project - LA 20 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6820 - DCRRNI ID/PEst-C%2FEQB%2FLA0020%2F2011/PT
oaire.citation.conferencePlaceBraga, Portugalpor
oaire.citation.title1st Symposium on Medicinal Chemistry of University of Minhopor
oaire.fundingStream6820 - DCRRNI ID
person.familyNameBarros
person.familyNameFernandes
person.familyNameFerreira
person.familyNameBarreiro
person.givenNameLillian
person.givenNameIsabel P.
person.givenNameIsabel C.F.R.
person.givenNameFilomena
person.identifier469085
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
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person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id3418-47D5-5746
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-0069-4503
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-6844-333X
person.identifier.ridJ-3600-2013
person.identifier.ridL-1552-2016
person.identifier.ridE-8500-2013
person.identifier.ridL-9802-2014
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id26323585300
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id57188719717
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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