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Development of stimuli-responsive smart hydrogels using molecular imprinting and interpenetrating polymer networks

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dc.contributor.authorOliveira, Tânia
dc.contributor.authorReitor, Patrícia
dc.contributor.authorOliveira, Daniela
dc.contributor.authorKadhirvel, Porkodi
dc.contributor.authorDias, Rolando
dc.contributor.authorCosta, Mário Rui
dc.date.accessioned2014-09-15T09:31:39Z
dc.date.available2014-09-15T09:31:39Z
dc.date.issued2014
dc.description.abstractDifferent classes of stimuli-responsive smart hydrogels (SRSH) were synthesized in order to assess the usefulness of molecular imprinting and generation of interpenetrating polymer networks to obtain advanced materials with tailored properties/performance. Reversible Addition-Fragmentation Chain-Transfer (RAFT) polymerisation was exploited as an additional tool to increase the control on the formation process of these materials. Batch adsorption and frontal analysis (e.g. for 3-aminopyridine (3AMP) as depicted in the graphical abstract) techniques were used to quantify the affinity of different drugs with the produced SRSH. Stimulated drug release (e.g. due to temperature/pH changes) and protein immobilisation/release were also tested. Results obtained show that molecular imprinting and generation of interpenetrating networks are effective routes to obtain tailored materials with a particular affinity to selected template molecules.por
dc.description.sponsorshipFCT and FEDER under Programme COMPETE (Project PEst-C/EQB/LA0020/2013), QREN, ON2 and FEDER (Project NORTE-07-0162-FEDER-000050) and QREN, ON2 and FEDER (Project NORTE-07-0124-FEDER- 0000014 - Polymer Reaction Engineering).por
dc.identifier.citationOliveira, Tânia; Reitor, Patrícia; Oliveira, Daniela; Kadhirvel, Porkodi; Dias, Rolando; Costa, Mário (2014). Development of stimuli-responsive smart hydrogels using molecular imprinting and interpenetrating polymer networks. In Chempor 2014. Porto, Portugalpor
dc.identifier.urihttp://hdl.handle.net/10198/10427
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherFEUP Ediçõespor
dc.relationFEDER (Project NORTE-07-0124-FEDER- 0000014 - Polymer Reaction Engineering).por
dc.relation.publisherversionhttp://chempor.ordemengenheiros.pt/pt/por
dc.subjectMolecular imprintingpor
dc.subjectInterpenetrating polymerspor
dc.subjectStimuli-responsivepor
dc.subjectHydrogelspor
dc.titleDevelopment of stimuli-responsive smart hydrogels using molecular imprinting and interpenetrating polymer networkspor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePorto, Portugalpor
oaire.citation.endPage12-107por
oaire.citation.startPage12-105por
oaire.citation.titleChempor 2014por
oaire.citation.volumeChempor 2014por
person.familyNameDias
person.givenNameRolando
person.identifier.ciencia-id8417-4D84-973B
person.identifier.orcid0000-0001-7369-382X
person.identifier.ridM-8552-2013
person.identifier.scopus-author-id7102885104
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublicationd7109687-6adf-4268-a462-8d1a2e2c01cb
relation.isAuthorOfPublication.latestForDiscoveryd7109687-6adf-4268-a462-8d1a2e2c01cb

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