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Enhancement of Bioactivity of Natural Extracts by Non-Thermal High Hydrostatic Pressure Extraction

dc.contributor.authorScepankova, Hana
dc.contributor.authorMartins, Margarida
dc.contributor.authorEstevinho, Leticia M.
dc.contributor.authorDelgadillo, Ivonne
dc.contributor.authorSaraiva, Jorge A.
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2019-02-04T16:58:57Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2019-02-04T16:58:57Z
dc.date.issued2018
dc.description.abstractNatural extracts, likethose obtained from medicinal herbs, dietary plantsand fruitsare being recognized as important sources of bioactive compounds with several functionalities including antioxidant, anticancer, and antimicrobial activities. Plant extracts rich in phenolic antioxidants are currently being successfully used for several pharmaceutical applications and in the development of new foods(i.e.,functional foods),in order to enhance the bioactivity of the products and to replace synthetic antioxidants.The extraction method applied in the recovery of the bioactive compounds from natural materials is a key factor to enhance the bioactivity of the extracts. However, most of the extraction techniques have to employ heat, which can easily lead to heat sensitive compounds losing their biological activity, due to changes caused by temperature. Presently, high hydrostatic pressure (HHP)is being increasingly explored as a cold extraction method of bioactive compounds from natural sources.This non-thermal high hydrostatic pressure extraction (HHPE) technique allows one to reduce the extraction time and increase the extraction of natural beneficial ingredients, in terms of nutritional value and biological activities and thus enhance the bioactivity of the extracts.This review provides an updated and comprehensive overview on the extraction efficiency of HHPE for the production of natural extracts with enhanced bioactivity,based on the extraction yield,total content and individual composition of bioactive compounds, extraction selectivity, and biological activities of the different plant extracts, so far studied by extraction with this technique.en_EN
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT) of Portugal for the PhD grants attributed to H. Scepankova (SFRH/BD/88133/2012) and M. Martins (SFRH/BD/ 122220/2016) and to FCT/MEC for the financial support to the QOPNA research Unit (FCT UID/QUI/00062/2013), through national funds and where applicable co-financed by the FEDER, within the PT2020 Partnership Agreement.
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationScepankova, Hana; Martins, Margarida; Estevinho, Leticia M.; Delgadillo, Ivonne; Saraiva, Jorge A. (2018). Enhancement of Bioactivity of Natural Extracts by Non-Thermal High Hydrostatic Pressure Extraction. Plant Foods for Human Nutrition. ISSN 0921-9668. 73, p. 253-267en_EN
dc.identifier.doi10.1007/s11130-018-0687-9en_EN
dc.identifier.issn0921-9668
dc.identifier.urihttp://hdl.handle.net/10198/18647
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationUSE OF HIGH PRESSURE TO DEVELOP A NON-THERMAL PASTEURIZED HONEY WITH UNIQUE FUNCTIONAL AND QUALITY CHARACTERISTICS
dc.relationScale-up of the extraction and purification of phycobiliproteins from Gracilaria sp. and their application as optically active centers in luminescent solar concentrators
dc.subjectAntioxidant activityen_EN
dc.subjectExtractionen_EN
dc.subjectHigh hydrostatic pressureen_EN
dc.subjectNatural extracten_EN
dc.subjectPhenolic compoundsen_EN
dc.titleEnhancement of Bioactivity of Natural Extracts by Non-Thermal High Hydrostatic Pressure Extractionen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleUSE OF HIGH PRESSURE TO DEVELOP A NON-THERMAL PASTEURIZED HONEY WITH UNIQUE FUNCTIONAL AND QUALITY CHARACTERISTICS
oaire.awardTitleScale-up of the extraction and purification of phycobiliproteins from Gracilaria sp. and their application as optically active centers in luminescent solar concentrators
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F00062%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F88133%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F122220%2F2016/PT
oaire.fundingStream5876
person.familyNameEstevinho
person.givenNameLetícia M.
person.identifier.ciencia-idBA14-09D6-A406
person.identifier.orcid0000-0002-9249-1948
person.identifier.scopus-author-id6506577664
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
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relation.isAuthorOfPublication.latestForDiscovery4a1d5ba2-1854-4ca5-89a4-73f35e964df9
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