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Wild Ginkgo biloba L. infusion supplies a higher amount of tocopherols than dietary supplements based on the same plant

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dc.contributor.authorPereira, Eliana
dc.contributor.authorBarros, Lillian
dc.contributor.authorBatista, Eugénia
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2013-09-09T10:21:31Z
dc.date.available2013-09-09T10:21:31Z
dc.date.issued2013
dc.description.abstractThe oxidative stress has a very high input in the development of neuritic abnormalities (1]. The powerful action exerted by Ginkgo bilobaL on cerebral vascular activity led to an increasing interest on its medicinal potential, mainly related to antioxidant properties (2]. Tocopherols are known to be powerful antioxidants through free radicals scavenging activity that allows the inhibition of lipid peroxidation. They reactwith peroxyl radicals produced from polyunsaturated fatty acids in membrane phospholipids or lipoproteins to yield stable lipid hydroperoxides (3].The purpose of this study was to evaluate the amount and profile of tocopherols in different dietary supplements: pills based on G. biloba leaves standardized extract with 24% glycosides and 6% terpenes (P1, 40 mg/pill ; P2,60 mg/pill; and P3, 100 mg/pill); oral solution (OS- 40 mg of G. biloba standardized extracVmL); and compare them with the infusion of G. bi/obawild leaves (LI) . Tocopherols were identified and quantified by high performance liquid chromatography coupled to a fluorescence detector (HPLC-fluorescence). All the vitamersa-, [3- , y-and a-tocopherol were found in the infusion but not in the dietary supplements. Furthermore, the infusion gave the highest amount of total tocopherols ( 126.23 mg/1 OOg dw) and of each individual vitamer; α- tocopherol was by far the most abundant tocopherol in that sample (124.88 mg/1 OOg dw). This study showed that wild G. biloba infusion supplies a much higher amount of tocopherols than dietary supplements based on the same plant. Moreover, its consumption could be beneficialdue to tocopherols free radicals scavenging activity and related protection to human body against degenerative abnormalities.por
dc.description.sponsorshipFCT for financial support to CIMO (strategic project PEstOE/ AGR/UI0690/2011 ). L. Barros also thanks to FCT, POPH-QREN and FSE for her grant (SFRH/BPD/4609/2008).por
dc.identifier.citationPereira, Eliana, Barros, Lillian; Batista, Eugénia; Ferreira, Isabel C.F.R. (2013). Wild Ginkgo biloba L. infusion supplies a higher amount of tocopherols than dietary supplements based on the same plant. In 1st Symposium on Medicinal Chemistry. Bragapor
dc.identifier.urihttp://hdl.handle.net/10198/8666
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationPEstOE/AGR/UI0690/2011
dc.relationSFRH/BPD/4609/2008
dc.titleWild Ginkgo biloba L. infusion supplies a higher amount of tocopherols than dietary supplements based on the same plantpor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceBraga, Portugalpor
oaire.citation.title1st Symposium on Medicinal Chemistry of University of Minhopor
person.familyNamePereira
person.familyNameBarros
person.familyNameFerreira
person.givenNameEliana
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-idBE17-462D-9A75
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-2854-6745
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridQ-8017-2018
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id55938912300
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8

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