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Chemical characterization and bioactivity evaluation of black mulberry and grape seeds

dc.contributor.authorGómez-Mejía, Esther
dc.contributor.authorRoriz, Custódio Lobo
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorDias, Maria Inês
dc.contributor.authorPinela, José
dc.contributor.authorRosales-Conrado, Noelia
dc.contributor.authorLeón-González, María Eugenia
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.date.accessioned2022-01-25T11:57:04Z
dc.date.available2022-01-25T11:57:04Z
dc.date.issued2021
dc.description.abstractCircular economy is increasingly seen as a crucial way to reduce food by- products and residues and obtain valuable raw materials. There is a growing demand for industrial products with clean labels and bio benefits, where natural bioactive compounds play an important role. Among these natural biomolecules, polyphenols stand out for their health benefits against diseases such as cancer or diabetes. Thus, the use of agro-industrial bioresidues as a rich source of polyphenols for the development of new natural preservatives, colorants and nutraceuticals is in the spotlight [1,2]. The aim of this work was the recovery of polyphenols from grape and mulberry seeds, usually considered as biowaste. Polyphenols were characterized by HPLC-DAD- ESI/MSn, and the obtained polyphenol-rich extracts were analysed for their bioactive properties, namely antimicrobial and antioxidant capacities. Grape seeds were richer in catechin oligomers (36.0 ± 0.3 mg/g), and mulberry seeds in ellagic acid derivatives (3.14 ± 0.02 mg/g). In addition, both extracts exhibited high antimicrobial activity against multi-resistant Staphylococcus aureus. On the other hand, mulberry seeds showed the strongest antioxidant activity by the lipid peroxidation inhibition (IC50 = 23 ± 2 μg/mL) and oxidative haemolysis inhibition (IC50 at a 60 min Δt = 46.0 ± 0.8 μg/mL) methods [2]. Both by-products could be exploited for the recovery of added-value bioactive polyphenols and further application in the industry [2].pt_PT
dc.description.sponsorshipThis work has been supported by Foundation for Science and Technology (FCT, Portugal) by national funds FCT/MCTES to CIMO (UIDB/00690/2020); the C.L. Roriz PhD’s grant (SFRH/BD/117995/2016), the contracts of M.I. Dias, R.C. Calhelha and L. Barros through the institutional scientific employment program-contract and S.A. Heleno (CEECIND/03040/2017) and J. Pinela (CEECIND/01011/2018) through the individual scientific employment program-contract. Eramus + grant (PBRAGAC01) and Complutense University of Madrid, Spain for the grant [CT17/17-CT18/17] of E. Gómez- Mejía. Ponto Agricola Lda. (Portugal) and Terras Gaudas (Spain) for providing the samples. European Regional Development Fund (ERDF) through the Regional Operational Program North 2020, within the scope of project GreenHealth (Norte-01-0145-FEDER-000042.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGómez-Mejía, Esther; Roriz, Custódio Lobo; Heleno, Sandrina A.; Calhelha, Ricardo C.; Dias, Maria Inês; Pinela, José; Rosales-Conrado, Noelia; León-González, M. Eugenia; Ferreira, Isabel C.F.R.; Barros, Lillian (2021). Chemical characterization and bioactivity evaluation of black mulberry and grape seeds. In 1st International Meeting for Young Analytical Chemists. ISBN 978-83-65955-53-1pt_PT
dc.identifier.issn978-83-65955-53-1
dc.identifier.urihttp://hdl.handle.net/10198/24898
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationCEECIND/03040/2017pt_PT
dc.relationMountain Research Center
dc.relationDevelopment of a new colouring agent from Gomphrena globosa L.: optimization of the extraction process, stability studies and proof-of-concept in a food matrix
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBioactivitypt_PT
dc.subjectPolyphenolspt_PT
dc.subjectBy-productspt_PT
dc.subjectGrape/mulberry seedspt_PT
dc.titleChemical characterization and bioactivity evaluation of black mulberry and grape seedspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardTitleDevelopment of a new colouring agent from Gomphrena globosa L.: optimization of the extraction process, stability studies and proof-of-concept in a food matrix
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_NORTE/SFRH%2FBD%2F117995%2F2016/PT
oaire.citation.title1st International Meeting for Young Analytical Chemistspt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPOR_NORTE
person.familyNameRoriz
person.familyNameHeleno
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person.givenNameCustódio Lobo
person.givenNameSandrina A.
person.givenNameRicardo C.
person.givenNameMaria Inês
person.givenNameJosé
person.givenNameIsabel C.F.R.
person.givenNameLillian
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project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
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