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Improving the bioactivity of medicinal plants using gamma radiation: Thymus vulgaris L. infusions as a case-study

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dc.contributor.authorPereira, Eliana
dc.contributor.authorBarros, Lillian
dc.contributor.authorAntonio, Amilcar L.
dc.contributor.authorCabo Verde, Sandra
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorOliveira, Beatriz
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-02-12T14:39:17Z
dc.date.available2018-02-12T14:39:17Z
dc.date.issued2017
dc.description.abstractThe bioactive compounds present in medicinal plants have shown beneficiai effects in the prevention of various diseases due to their capacity to act positively in several biological mechanisms [1] with reduced adverse effects [2]. The aim of this work was to evaluate the effects of gamma radiation processing, at doses of 1 and 10 kGy, on antioxidant activity and phenolic composition of a medicinal plant used m traditional medicine - fhymus vulgaris L., and the results compared with the contrai sample (O kGy). After plants processing, an infusion was prepared, from irradiated and non-irradiated samples to evaluate antioxidant properties through: free radicais scavenging activity, reducing power and inhibition of lipid peroxidation in brain cell homogenates (TBARS assay) methods. And phenolic compounds were analysed by HPLC-DAD-ESI/MS. Com"paring'the results obtained for contrai (O kGy) and irradiated samples (at 1 and 10 kGy), it was evident that gamma irradiation at the dose of 10 kGy improved free radical scavenging actiyity, reducing power and lipid peroxidation inhibition capacity of the infusions (lower values of EÇso). RegardFng phenolics, thirteen compounds were detected in the infusions prepared either from irradiated or non-irradiated samples. However, the global phenolic profile was not changed. In this way, gamma radiation could be considered as a suitable treatment to be used in dried plants in particular, to improve bioactive properties of Thymus vulgaris L. related to its phenolic composition [3].pt_PT
dc.description.sponsorshipFoundation for Science and Technology (FCT, Portugal) for financiai support to CIMO (PEst-OE/AGR/UI0690/2013), CTN (RECI/AAG-TEC/0400/2012), REQUIMTE (UID/QUI/50006/2013 - POCI/01/0145/ FERDER/007265) and L. Barms grant (BPD/107855/2015). The auíhors are also grateful to "MaisEn/as - Aromáticas e Medicinais" company for pmvidiry lhe samples.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.citationPereira, Eliana; Barros, Lillian; Antonio, Amilcar L.; Cabo Verde, Sandra; Santos-Buelga, Celestino: Oliveira, M.B.P.P.; Ferreira, Isabel C.F.R. (2017). Improving the bioactivity of medicinal plants using gamma radiation: Thymus vulgaris L. infusions as a case-study. In 3rd Symposium on Medicinal Chemistry of University of Minho. Bragapt_PT
dc.identifier.urihttp://hdl.handle.net/10198/15683
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationPEst-OE/AGR/UI0690/2013pt_PT
dc.relationApplication of Ionizing Radiation for a Sustainable Environment
dc.relationBPD/107855/2015pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleImproving the bioactivity of medicinal plants using gamma radiation: Thymus vulgaris L. infusions as a case-studypt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardNumberRECI/AAG-TEC/0400/2012
oaire.awardNumberUID/QUI/50006/2013
oaire.awardTitleApplication of Ionizing Radiation for a Sustainable Environment
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/RECI%2FAAG-TEC%2F0400%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F50006%2F2013/PT
oaire.citation.conferencePlaceBraga, Portugalpt_PT
oaire.citation.title3rd Symposium on Medicinal Chemistry of University of Minhopt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStream5876
person.familyNamePereira
person.familyNameBarros
person.familyNameAntonio
person.familyNameFerreira
person.givenNameEliana
person.givenNameLillian
person.givenNameAmilcar L.
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-idBE17-462D-9A75
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id1014-5259-DE86
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-2854-6745
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0001-8271-9964
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridQ-8017-2018
person.identifier.ridJ-3600-2013
person.identifier.ridJ-1960-2014
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id55938912300
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id44560921900
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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