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Bioactivity of the Geranium Genus: a Comprehensive Review

dc.contributor.authorGraça, Vânia C.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorSantos, Paulo F.
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2020-06-22T10:18:54Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2020-06-22T10:18:54Z
dc.date.issued2020
dc.description.abstractBackground: Plants from the Geranium genus, which comprises about 400 species, have been used since ancient times in the practice of traditional medicines throughout the world. Therefore, herbal preparations based on Geranium species have found wide usage for the treatment of a variety of ailments. The aim of this work is to present a review, as comprehensive as possible, of the studies concerning different biological activities of Geranium species. Methods: Relevant data were obtained through systematic computer searches from major reputed scientific databases, particularly Web of Science and Scopus. Occasionally, information issued in primary sources not covered by these databases was also included provided published as peer-reviewed literature. This review covers the literature disclosed till the end of 2018. Results: Accompanying the increasing interest in herbal medicines in general, the evaluation of the biological properties of medicinal plants from the Geranium genus has been addressed thoroughly, mostly over the last two decades. Geranium species are endowed with a number of different biological activities. Herein, we present a survey of the results of the studies concerning these different biological activities. Conclusion: Most studies found in the literature effectively contribute to scientifically validate the beneficial properties of Geranium plants claimed by traditional medicines and medical herbalism and demonstrate that many of them possess evident therapeutic properties.
dc.description.sponsorshipThis work was supported by European Investment Funds by FEDER/COMPETE/POCI - Operational Competitiveness and Internationalization Programme, under Project POCI-01-0145- FEDER-006958 and National Funds by FCT - Portuguese Foundation for Science and Technology under the projects UID/AGR/00690/2013 (CIMO) and UID/QUI/00616/2013 (CQ-VR). V.C. Graça thanks FCT for her grant (SFRH/BD/52542/2014). The authors are also grateful to Interreg España-Portugal for financial support through the project 0377_Iberphenol_6_E.
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationGraça, Vânia C.; Ferreira, Isabel C.F.R.; Santos, Paulo F. (2020). Bioactivity of the Geranium Genus: a comprehensive review. Current pharmaceutical design. ISSN 1381-6128. 26:16, p. 1838-1865en_EN
dc.identifier.doi10.2174/1381612826666200114110323en_EN
dc.identifier.urihttp://hdl.handle.net/10198/22350
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.subjectAilmentsen_EN
dc.subjectBiological propertiesen_EN
dc.subjectGeranium speciesen_EN
dc.subjectHerbalismen_EN
dc.subjectMedicinal plantsen_EN
dc.subjectSpeciesen_EN
dc.titleBioactivity of the Geranium Genus: a Comprehensive Reviewen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F00616%2F2013/PT
oaire.fundingStream5876
oaire.fundingStream5876
person.familyNameFerreira
person.givenNameIsabel C.F.R.
person.identifier144781
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
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relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8
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