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Phenolic compounds among the bioactive molecules in Ginkgo biloba L.

dc.contributor.authorPereira, Eliana
dc.contributor.authorBarros, Lillian
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2015-11-19T15:09:04Z
dc.date.available2015-11-19T15:09:04Z
dc.date.issued2015
dc.description.abstractThe interest for natural antioxidants has been increasing over the years. Phenolic compounds comprise a very large group of biologically active molecules, being appreciated for their beneficial effects on health (physiologically active compounds with anti-allergic, antiatherogenic, antimicrobial, antithrombotic, anti-inflammatory, antioxidant, cardioprotective and vasodilatory effects) [1-3]. The aim of the present study was to evaluate the phenolic compounds of Ginkgo biloba L. (infusion and methanol/water extract), widely used in traditional medicine and in dietary supplements. Twenty-five compounds were detected, eighteen of which were flavonoids, one phenolic acid, five terpene lactones and one unknown compound. However, among the twenty-five compounds detected, compounds 1, 2, 4-6 and 12, associated to ginkgolides, were not quantified due their low UV absorption and possible interferences in the complex matrix of G. biloba extracts, as well as the unavailability of commercial gingkolide standards. Regarding the quantified phenolic compounds, flavonoids were the main group present, being two kaempferol derivatives the major compounds found: kaempferol-3-0-dirhamnosylglucoside and kaempferol-3-O-rutinoside. The infusion presented lower quantities than the methanol/water extract, probably due to the high temperatures applied to obtain the first preparation that could have destroyed some thermal sensitive compounds, but also due to the lower extraction time.pt_PT
dc.identifier.citationPereira, Eliana; Barros, Lillian; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2015). Phenolic compounds among the bioactive molecules in Ginkgo biloba L. In 2nd Symposium on Medicinal Chemistry of University of Minhopt_PT
dc.identifier.urihttp://hdl.handle.net/10198/12376
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationProder 53514 - AROMAPpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titlePhenolic compounds among the bioactive molecules in Ginkgo biloba L.pt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardNumberPEst-OE/AGR/UI0690/2014
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/PEst-OE%2FAGR%2FUI0690%2F2014/PT
oaire.citation.title2nd Symposium on Medicinal Chemistry of University of Minhopt_PT
oaire.fundingStream5876
person.familyNamePereira
person.familyNameBarros
person.familyNameFerreira
person.givenNameEliana
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-idBE17-462D-9A75
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-2854-6745
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridQ-8017-2018
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id55938912300
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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