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Antibacterial activity of Euterpe oieracea Mart. seeds against clinical isolates

2015Documento de conferência Acesso aberto
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dc.contributor.authorAlves, Maria José
dc.contributor.authorPimentel, Maria Helena
dc.contributor.authorBaía, Lilia
dc.contributor.authorSoares, R.P.
dc.contributor.authorSantos, C.R.
dc.contributor.authorRegis, Wiliam C.B.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2016-01-15T15:23:50Z
dc.date.available2016-01-15T15:23:50Z
dc.date.issued2015
dc.description.abstractIntroduction: The use of antibiotics – including the over- and misuse – in human and veterinary practices selected for resistant pathogens led to their emergence and dissemination along with the transmission of resistant bacteria [1]. Due to this problem, there is a need to investigate new strategies to reverse this tendency in order to achieve the appropriate and effective treatment against infections. Aims: The present work aimed to evaluate the antibacterial activity of an aqueous extract prepared from Euterpe Oleracea Mart. (açai) seeds (originated from Brazil [2]), against clinical isolates from “Centro Hospitalar de Trás-os-Montes e Alto Douro- Unidade de Vila Real”, with high resistance profiles to different antibiotics. Material and Methods: The minimal inhibitory concentrations (MIC) of the growth of Gram-positive and Gram-negative bacteria were determined by the colorimetric assay based on the use of p-iodonitrotetrazolium chloride (INT) dye, after application of the microdilution method. Results and discussion: The açaí aqueous extract showed antimicrobial activity against all the tested Gram-positive bacteria. The lowest MICs (0.25 mg/ml) were obtained against Methicillin Susceptible Staphylococcus aureus (MSSA) and Methicillin Resistant S. aureus (MRSA), followed by the MIC 0.5 mg/ml correspondent to Streptococcus agalactiae and Enterococcus faecalis. Regarding the inhibition of the growth of Gram-negative bacteria, the extract was active against Morganella morganii, Pseudomonas aeruginosa and Acinetobacter baumannii with MICs 1 mg/ml e 2 mg/ml, respectively. The results were better for Gram-positive bacteria in comparison with Gram-negative bacteria. Conclusion: However, even at low concentration (2 mg/ml) the results are very promising for Gram-negative bacteria with high resistance profiles and commonly related with health care-associated infections, namely Pseudomonas aeruginosa and Acinetobacter baumannii.pt_PT
dc.identifier.citationAlves, Maria José; Pimentel, Helena; Baía, L.A.; Soares, R.P.; Santos, C.R.; Regis, Wiliam C.B.; Ferreira, Isabel C.F.R. (2015). Antibacterial activity of Euterpe oieracea Mart. seeds against clinical isolates. In II Congresso Internacional de Saúde Gaia-Porto - "Do Diagnóstico à Intervenção. Portopt_PT
dc.identifier.urihttp://hdl.handle.net/10198/12604
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectClinical isolatespt_PT
dc.subjectMultiresistancept_PT
dc.subjectAçaí seedspt_PT
dc.subjectAntibacterial activitypt_PT
dc.titleAntibacterial activity of Euterpe oieracea Mart. seeds against clinical isolatespt_PT
dc.typeconference object
dspace.entity.typePublication
person.familyNameAlves
person.familyNamePimentel
person.familyNameFerreira
person.givenNameMaria José
person.givenNameMaria Helena
person.givenNameIsabel C.F.R.
person.identifier144781
person.identifier.ciencia-idD618-B3A9-D312
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0001-8506-4393
person.identifier.orcid0000-0002-0930-7469
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridM-6624-2016
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id16400584800
person.identifier.scopus-author-id36868826600
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication7850f8c2-8834-4d5a-b4a7-df482abd76d3
relation.isAuthorOfPublication4fc182c0-1925-4c27-92c2-5a4bd06680c5
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscovery7850f8c2-8834-4d5a-b4a7-df482abd76d3

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