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Red blood cell motions in high-hematocrit blood flowing through a stenosed microchannel

dc.contributor.authorFujiwara, Hiroki
dc.contributor.authorIshikawa, Takuji
dc.contributor.authorLima, Rui A.
dc.contributor.authorMatsuki, Noriaki
dc.contributor.authorImai, Yohsuke
dc.contributor.authorKaji, Hirokazu
dc.contributor.authorNishizawa, Matsuhiko
dc.contributor.authorYamaguchi, Takami
dc.date.accessioned2010-01-23T17:53:20Z
dc.date.available2010-01-23T17:53:20Z
dc.date.issued2009
dc.description.abstractWe investigated the behaviour of red blood cells (RBCs) in a micro-channel with stenosis by using a confocal micro-PIV system. We could successfully measure individual trajectories of RBCs in a concentrated suspension up to 20% hematocrit (Hct). The results show that the trajectories of healthy RBCs become asymmetric before and after the stenosis, though trajectories of tracer particles in pure water are almost symmetric. The asymmetry is larger in a 10% Hct case than in a 20% Hct case. We also investigated the effect of deformability of RBCs on the trajectories by hardening RBCs by glutarardehyde treatment. The results indicate that the deformability is the key factor in the asymmetry of trajectories and the thickness of cell-free layer. We think that the present results give fundamental knowledge for better understanding blood flow in microcirculations.pt
dc.identifier.citationFujiwara, H.; Ishikawa, T.; Lima, R.; Matsuki, N.; Imai, Y.; Kaji, H.; Nishizawa, M.; Yamaguchi, T. (2009). Red blood cell motions in high-hematocrit blood flowing through a stenosed microchannel. Journal of Biomechanics. ISSN 0021-9290. 42:7, p.838-843pt
dc.identifier.issn0021-9290
dc.identifier.urihttp://hdl.handle.net/10198/1422
dc.language.isoengpt
dc.publisherElsevierpt
dc.subjectRed blood cellspt
dc.subjectMicrochannelpt
dc.subjectStenosispt
dc.subjectMicrocirculationpt
dc.titleRed blood cell motions in high-hematocrit blood flowing through a stenosed microchannelpt
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleJournal of Biomechanicspt
person.familyNameLima
person.givenNameRui A.
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.orcid0000-0003-3428-637X
person.identifier.ridH-5157-2016
person.identifier.scopus-author-id18437397800
rcaap.rightsopenAccesspt
rcaap.typearticlept
relation.isAuthorOfPublication7b50c499-8095-4f4f-8b1b-fa7388e4ff62
relation.isAuthorOfPublication.latestForDiscovery7b50c499-8095-4f4f-8b1b-fa7388e4ff62

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