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Lamiaceae often used in Portuguese folk medicine as a source of powerful antioxidants: vitamins and phenolics

2010Journal article Restricted access
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dc.contributor.authorBarros, Lillian
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorCarvalho, Ana Maria
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2010-10-28T14:52:40Z
dc.date.available2010-10-28T14:52:40Z
dc.date.issued2010
dc.description.abstractThree Lamiaceae often used in Portuguese folk medicine: Ground ivy (Glechoma hederaceae L.), oregano (Origanum vulgare subsp. virens (Hoffmanns. & Link) Ietswaart) and mastic thyme (Thymus mastichina L.), revealed to be good sources of powerful antioxidants such as vitamins (ascorbic acid and tocopherols) and phenolics. The HPLC methodology developed for tocopherols analysis proved to be, after validation assays, sensitive and accurate. Ground ivy showed the highest levels of vitamins: ascorbic acid (168 2 mg/g dry weight) and tocopherols (3692 57 mg/g dry weight). The phenolics extraction was optimized using mastic tyme, and different conditions (water and ethanol:water 50% v/v, 30 min at 25 C and boiling temperature; ethanol and methanol, 24 h at 25 C). The best methodology (25 C, 50 ml of methanol, 24 h) was further applied to the other Lamiaceae. Oregano proved to have the highest radical scavenging and lipid peroxidation inhibition capacity. Particularly, the very low EC50 value (0.01 mg/ml) obtained for TBARS inhibition in brain homogenates is very promising, considering that brain is highly sensitive to oxidative damage. Significantly negative linear correlations were observed between phenolics, including flavonoids, and antioxidant activity EC50 values of the three Lamiaceae.por
dc.identifier.citationBarros, Lillian; Heleno, Sandrina; Carvalho, Ana Maria; Ferreira, ICFR (2010). Lamiaceae often used in Portuguese folk medicine as a source of powerful antioxidants: vitamins and phenolics. LWT - Food Science and Technology. ISSN 0023-6438. 43:3. p. 544-550por
dc.identifier.doi10.1016/j.lwt.2009.09.024
dc.identifier.issn0023-6438
dc.identifier.urihttp://hdl.handle.net/10198/2716
dc.language.isoengpor
dc.publisherElsevierpor
dc.relationEthnobotany of the Northeastern Region of Portugal: local knowledge, plants and uses
dc.relationEMBEDDED SYSTEMS FOR ELLIPTIC CURVE
dc.subjectLamiaceaepor
dc.subjectVitaminspor
dc.subjectHPLC validationpor
dc.subjectRadical scavenging capacitypor
dc.subjectLipid peroxidation inhibitionpor
dc.subjectPortuguese ethnobotany
dc.titleLamiaceae often used in Portuguese folk medicine as a source of powerful antioxidants: vitamins and phenolicspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEthnobotany of the Northeastern Region of Portugal: local knowledge, plants and uses
oaire.awardTitleEMBEDDED SYSTEMS FOR ELLIPTIC CURVE
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POCI/POCI%2FANT%2F59395%2F2004/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/PIDDAC/SFRH%2FBD%2F44609%2F2008/PT
oaire.citation.endPage550por
oaire.citation.startPage544por
oaire.citation.titleLWt - Food Science and Technologypor
oaire.fundingStreamPOCI
oaire.fundingStreamPIDDAC
person.familyNameBarros
person.familyNameHeleno
person.familyNameCarvalho
person.familyNameFerreira
person.givenNameLillian
person.givenNameSandrina A.
person.givenNameAna Maria
person.givenNameIsabel C.F.R.
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person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0001-7224-1098
person.identifier.orcid0000-0001-5508-5935
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridL-5951-2014
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id30067731800
person.identifier.scopus-author-id20336503900
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
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