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Antioxidant activity and phenolic compounds in decoction, infusion and hydroalcoholic extract of Origanum vulgare L.

dc.contributor.authorMartins, Natália
dc.contributor.authorBarros, Lillian
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2014-03-27T16:16:23Z
dc.date.available2014-03-27T16:16:23Z
dc.date.issued2013
dc.description.abstractReactive species, including free radicals, have been implicated in ageing and various diseases [1]. The human body possesses an antioxidant defense system that acts in the detoxification and elimination of those species. Nevertheless, natural matrices can give an exogenous contribution, providing antioxidant biomolecules such is the case of phenolic compounds [2]. Origanum vu/gore L. (oregano) could be one of those matrices since various studies already reported the antioxidant potential of its methanolic extract [for example, 3] and essential oils [for example, 4]. Nonetheless, the reports using aqueous extracts are scarce [5], mainly in decoction or infusion preparations traditionally used to their digestive, expectorant, antiseptic and antispasmodic properties. In the present work, the antioxidant properties (reducing power- RP, free radica ls scavenging activity- RSA and lipid peroxidation inhibition- LPI) and phenolic compounds of the infusion, decoction and hydroalcoholic extract of oregano (obtained from Soria Natural, Spain) were evaluated and compared. The infusion and decoction presented similar RP and RSA, showing the decoction higher LPI. Both preparations gave higher antioxidant activity than the hydroalcoholic extract. Twenty-two phenolic compounds were identified by HPLC-OAO-ESI/MS: seven phenolic acids (caffeoylquinic, syringic, protocatequic and rosmarinic acids, and derivatives), six flavonols (quercetin, kaempferol and myrecitrin derivatives), five flavones (apigenin and luteolin derivatives), one flavanonol (taxifolin) and one flavanone (eriodictyol). Rosmarinic acid and luteolin-7-0 -glucoside were the main phenolic acid and flavonoid, respectively, in all the preparations. Data obtained provide more scientific evidences to the traditional medicinal uses of oregano, mainly in the treatment of oxidative stress-associated diseases.por
dc.description.sponsorshipFCT and COMPETE/QREN/EU: strategic project PEst-OE/AGR/UI0690/2011 (CIMO); grant SFRH/BD/87658/2012 to N. Martins, and "Compromisso para a Ciencia 2008" contract of L. Barros.por
dc.identifier.citationMartins, Natália; Barros, Lillian; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2013). Antioxidant activity and phenolic compounds in decoction, infusion and hydroalcoholic extract of Origanum vulgare L. In 8º Encontro Nacional de Cromatografia. Covilhã: Universidade da Beira Interior. ISBN 978·989 ·98541· 1·6por
dc.identifier.urihttp://hdl.handle.net/10198/9394
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationStrategic Project - UI 690 - 2011-2012
dc.relationPLANTAS MEDICINAIS A UTILIZAR EM FITOTERAPIA COMO ANTI-FÚNGICOS: EFEITO DE COMPOSTOS FENÓLICOS NO CRESCIMENTO DE ESPÉCIES DE CANDIDA EM SUSPENSÃO E EM BIOFILMES
dc.titleAntioxidant activity and phenolic compounds in decoction, infusion and hydroalcoholic extract of Origanum vulgare L.por
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardTitlePLANTAS MEDICINAIS A UTILIZAR EM FITOTERAPIA COMO ANTI-FÚNGICOS: EFEITO DE COMPOSTOS FENÓLICOS NO CRESCIMENTO DE ESPÉCIES DE CANDIDA EM SUSPENSÃO E EM BIOFILMES
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F87658%2F2012/PT
oaire.citation.conferencePlaceCovilhã, Portugalpor
oaire.citation.title8º Encontro Nacional de Cromatografiapor
oaire.fundingStream6817 - DCRRNI ID
person.familyNameBarros
person.familyNameFerreira
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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