Repository logo
 
Publication

Multifunctions of Pleurotus sajor-caju (Fr.) Singer: a highly nutritious food and a source for bioactive compounds

2018Journal article Open access
Simple item page
dc.contributor.authorFinimundy, Tiane C.
dc.contributor.authorBarros, Lillian
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorAlves, Maria José
dc.contributor.authorPrieto Lage, Miguel A.
dc.contributor.authorAbreu, Rui M.V.
dc.contributor.authorDillon, Aldo J.P.
dc.contributor.authorHenriques, João A.P.
dc.contributor.authorRoesch-Ely, Mariana
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-01-29T10:00:00Z
dc.date.accessioned2018-01-29T10:39:39Z
dc.date.available2018-01-29T10:00:00Z
dc.date.available2018-01-29T10:39:39Z
dc.date.issued2018
dc.description.abstractA study with Pleurotus sajor-caju was conducted to: evaluate the nutritional and chemical composition of the fruiting bodies; optimize the preparation of bioactive phenolic extracts; and characterize the optimized extract in terms of bioactive compounds and properties. P. sajor-caju revealed an equilibrated nutritional composition with the presence of hydrophilic (sugars and organic acids) and lipophilic (tocopherols and PUFA) compounds. p-Hydroxybenzoic, p-coumaric and cinnamic acids were identified in the extract obtained with ethanol (30 g/l ratio) at 55 °C for 85 min. This extract showed antioxidant properties (mainly reducing power and lipid peroxidation inhibition), antibacterial activity against MRSA and MSSA and cytotoxicity against NCI-H460, MCF-7 and HeLa. Furthermore, as the extract showed capacity to inhibit NO production in Raw 264.7 macrophages, molecular docking studies were performed to provide insights into the anti-inflammatory mechanism of action, through COX-2 inhibition by the phenolic acids identified.pt_PT
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Program PT2020 for financial support to CIMO (UID/AGR/00690/2013) and for L. Barros and R. Calhelha contracts. T.C. Finimundy thanks CAPES Foundation, Ministry of Education of Brazil (CAPES fellow, process number 88881.134581/2016-01). To Xunta de Galicia for financial support for the post-doctoral researcher of M.A. Prieto.
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFinimundy, Tiane C.; Barros, Lillian; Calhelha, Ricardo C.; Alves, Maria José; Prieto, Miguel A.; Abreu, Rui M.V.; Dillon, Aldo J.P.; Henriques, João A.P.; Roesch-Ely, Mariana; Ferreira, Isabel C.F.R. (2018). Multifunctions of Pleurotus sajor-caju (Fr.) Singer: A highly nutritious food and a source for bioactive compounds. Food Chemistry. ISSN 0308-8146. 245, p. 150-158
dc.identifier.doi10.1016/j.foodchem.2017.10.088pt_PT
dc.identifier.issn03088146
dc.identifier.urihttp://hdl.handle.net/10198/15073
dc.language.isoeng
dc.peerreviewedyespt_PT
dc.titleMultifunctions of Pleurotus sajor-caju (Fr.) Singer: a highly nutritious food and a source for bioactive compoundsen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.fundingStream5876
person.familyNameFinimundy
person.familyNameBarros
person.familyNameCalhelha
person.familyNameAlves
person.familyNamePrieto Lage
person.familyNameAbreu
person.familyNameFerreira
person.givenNameTiane C.
person.givenNameLillian
person.givenNameRicardo C.
person.givenNameMaria José
person.givenNameMiguel A.
person.givenNameRui M.V.
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier107688
person.identifier144781
person.identifier.ciencia-id2F18-67B1-776A
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-idD618-B3A9-D312
person.identifier.ciencia-id221E-1E00-AB74
person.identifier.ciencia-id0F19-0DE2-12A2
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-3516-0795
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0001-8506-4393
person.identifier.orcid0000-0002-3513-0054
person.identifier.orcid0000-0002-7745-8015
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridJ-2172-2014
person.identifier.ridM-6624-2016
person.identifier.ridG-4516-2011
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id16400584800
person.identifier.scopus-author-id35937495700
person.identifier.scopus-author-id7003290613
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticlept_PT
relation.isAuthorOfPublication4f8767d4-4e62-4550-9b35-740cb2f672da
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication2d5d1a41-7561-4a01-871c-b4c97da35053
relation.isAuthorOfPublication7850f8c2-8834-4d5a-b4a7-df482abd76d3
relation.isAuthorOfPublication13260615-fd28-4b8b-9dd4-8a8466007579
relation.isAuthorOfPublicationcadb03a4-5e60-4745-b35f-fc3a97c071bc
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isProjectOfPublicationcfb6e380-87c4-4772-8c2c-76799a53d6df
relation.isProjectOfPublication.latestForDiscoverycfb6e380-87c4-4772-8c2c-76799a53d6df

Files

Collections

CIMO - Artigos em Revistas Indexados à WoS/Scopus