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Synthesis of aminodiarylamines in the thieno[3,2-b]pyridine series and effects on tumor cell growth inhibition, cell cycle and apoptosis

2011Conference object Open access
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dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorAbreu, Rui M.V.
dc.contributor.authorVale-Silva, Luís A.
dc.contributor.authorPinto, Eugénia
dc.contributor.authorLima, Raquel T.
dc.contributor.authorAlvelos, M. Inês
dc.contributor.authorVasconcelos, M. Helena
dc.contributor.authorQueiroz, Maria João R.P.
dc.date.accessioned2011-10-25T13:12:48Z
dc.date.available2011-10-25T13:12:48Z
dc.date.issued2011
dc.description.abstractSeveral series of compounds that include the thienopyridine scaffold have been reported as inhibitors of known cancer therapeutic targets or as inhibitors of cell proliferation in tumor cell lines [1,2]. Our research group has already synthesized several thieno[3,2-b]pyridine derivatives by Pd-catalyzed C-C (Suzuki and Sonogashira) and C-N (Buchwald-Hartwig) couplings and some of them have presented tumor cell growth inhibitory activity in cell lines [3- 5].por
dc.identifier.citationCalhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Abreu, Rui M.V.; Vale-Silva, Luís A.; Pinto, Eugénia; Lima, Raquel T.; Alvelos, M. Inês; Vasconcelos, M. Helena; Queiroz, Maria-João R.P. (2011). Synthesis of aminodiarylamines in the thieno[3,2-b]pyridine series and effects on tumor cell growth inhibition, cell cycle and apoptosis. In III Congress of the Portuguese Society of Pharmaceutical Sciences and IX Spanish-Portuguese conference on controlled drug delivery. Portopor
dc.identifier.urihttp://hdl.handle.net/10198/6241
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Ciências Farmacêuticaspor
dc.relationSMALL MOLECULES AS APOPTOSIS INDUCERS IN CANCER CELLS: INVESTIGATION OF THE MECHANISM OF ACTION
dc.titleSynthesis of aminodiarylamines in the thieno[3,2-b]pyridine series and effects on tumor cell growth inhibition, cell cycle and apoptosispor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleSMALL MOLECULES AS APOPTOSIS INDUCERS IN CANCER CELLS: INVESTIGATION OF THE MECHANISM OF ACTION
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F68787%2F2010/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FQUI-QUI%2F111060%2F2009/PT
oaire.citation.conferencePlacePortopor
oaire.citation.endPage78por
oaire.citation.startPage77por
oaire.citation.titleRevista Portuguesa de Farmácia; volume LII (nº6). 3rd Congress of the Portuguese Society of Pharmaceutical Sciences; 9th Portuguese-Spanish Conference on Controlled Drug Delivery; New Trends in Pharmaceutical Sciences, 13 a 15 de Outubro de 2011,por
oaire.fundingStream5876-PPCDTI
person.familyNameCalhelha
person.familyNameFerreira
person.familyNameAbreu
person.givenNameRicardo C.
person.givenNameIsabel C.F.R.
person.givenNameRui M.V.
person.identifier144781
person.identifier.ciencia-idF313-E3CE-554E
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person.identifier.ciencia-id0F19-0DE2-12A2
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person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-7745-8015
person.identifier.ridJ-2172-2014
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id7003290613
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
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