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Adulteration of Dietary Supplements by the Illegal Addition of Synthetic Drugs: a review

2016Journal article Open access
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dc.contributor.authorRocha, Tiago
dc.contributor.authorAmaral, Joana S.
dc.contributor.authorOliveira, Beatriz
dc.date.accessioned2018-01-31T10:00:00Z
dc.date.accessioned2018-02-01T09:38:00Z
dc.date.available2018-01-31T10:00:00Z
dc.date.available2018-02-01T09:38:00Z
dc.date.issued2016
dc.description.abstractIn the last few years, the consumption of dietary supplements, especially those having plants as ingredients, has been increasing due to the common idea that they are natural products posing no risks to human health. In the European Union and the United States, dietary supplements are legally considered as foods/special category of foods, thus are not being submitted to any safety assessment prior to their commercialization. Among the issues that can affect safety, adulteration by the illegal addition of pharmaceutical substances or their analogs is of major concern since unscrupulous producers can falsify these products to provide for quick effects and to increase sales. This review discusses the various classes of synthetic drugs most frequently described as being illegally added to dietary supplements marketed for weight loss, muscle building/sport performance and sexual performance enhancement. Information regarding regulation and consumption is also presented. Finally, several conventional and advanced analytical techniques used to detect and identify different adulterants in dietary supplements and therefore also in foods, with particular emphasis on plant food supplements, are critically described. This review demonstrates that dietary supplement adulteration is an emerging food safety problem and that an effective control by food regulatory authorities is needed to safeguard consumers.en_EN
dc.description.sponsorshipThis work was supported by European Union (FEDER funds through COMPETE) and Natl. Funds (FCT, Fundação para a Ciência e Tecnologia) through projects EXPL/DTP-SAP/1438/2013 (Safety of plant food supplements: searching for adulterant pharmaceutical drugs and plants) and LAQV UID/QUI/50006/2013.
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationRocha, Tiago; Amaral, Joana S.; Oliveira, Maria Beatriz P.P. (2016). Adulteration of Dietary Supplements by the Illegal Addition of Synthetic Drugs: A Review. Comprehensive Reviews in Food Science and Food Safety. ISSN 1541-4337. 15, p. 43-62en_EN
dc.identifier.doi10.1111/1541-4337.12173en_EN
dc.identifier.isbn1541-4337
dc.identifier.urihttp://hdl.handle.net/10198/15401
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.subjectAdulterationen_EN
dc.subjectAnalogsen_EN
dc.subjectDietary supplementsen_EN
dc.subjectFood safetyen_EN
dc.subjectPharmaceutical drugsen_EN
dc.subjectPlant food supplementsen_EN
dc.titleAdulteration of Dietary Supplements by the Illegal Addition of Synthetic Drugs: a reviewen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/COMPETE/EXPL%2FDTP-SAP%2F1438%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F50006%2F2013/PT
oaire.fundingStreamCOMPETE
oaire.fundingStream5876
person.familyNameAmaral
person.givenNameJoana S.
person.identifier.ciencia-id5319-7DE8-BEDA
person.identifier.orcid0000-0002-3648-7303
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublication42be2cf4-adc4-4e7f-ac60-7aab515b38cd
relation.isAuthorOfPublication.latestForDiscovery42be2cf4-adc4-4e7f-ac60-7aab515b38cd
relation.isProjectOfPublication730054a0-eed4-4013-806b-672d1d27b87d
relation.isProjectOfPublication40f15c30-b6e8-4474-ae1d-d7256c7af84e
relation.isProjectOfPublication.latestForDiscovery40f15c30-b6e8-4474-ae1d-d7256c7af84e

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