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Non-edible parts of Solanum stramoniifolium Jacq. - a new potent source of bioactive extracts rich in phenolic compounds for functional foods

2017Journal article Open access
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dc.contributor.authorSvobodova, Blanka
dc.contributor.authorBarros, Lillian
dc.contributor.authorSopik, Tomas
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorAlves, Maria José
dc.contributor.authorWalcott, Simone
dc.contributor.authorKuban, Vlastimil
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-01-25T10:00:00Z
dc.date.accessioned2018-01-30T15:00:28Z
dc.date.available2018-01-25T10:00:00Z
dc.date.available2018-01-30T15:00:28Z
dc.date.issued2017
dc.description.abstractExtracts prepared from leaves, roots, and stems of Solanum stramoniifolium Jacq. (Solanaceae) in 80% ethanol have been tested for their in vitro antioxidant, anti-inflammatory, antimicrobial, and cytotoxic activities with an aim to find new sources of substances for functional foods and food additives. The root extract revealed the highest antioxidant activity in all assays exceeding the trolox capacity, and was the only extract that inhibited nitric oxide production in mouse macrophage cells, showing also the capacity to suppress the growth of all tested human tumor cell lines (MCF-7, NCI-H460, HeLa and HepG2). The leaf extract showed the strongest antimicrobial activity inhibiting all tested clinical isolates. To the author's best knowledge it was the first time that all individual parts of this plant were tested for biological activity together with the phenolic compound characterization.pt_PT
dc.description.sponsorshipThe authors thank the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2013) and L. Barros (SFRH/BPD/107855/2015), S. Heleno (SFRH/BPD/ 101413/2014) and R. C. Calhelha (SFRH/BPD/BPD/68344/2010) grants. To POCI-01-0145-FEDER-006984 (LA LSRE-LCM), funded by FEDER, through POCI-COMPETE2020 and FCT. This study was financially supported by Internal Grant Agency of Tomas Bata University in Zlin, project no. IGA/FT/2016/003.
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSvobodova, Blanka; Barros, Lillian; Sopik, Tomas; Calhelha, Ricardo C.; Heleno, Sandrina; Alves, Maria Jose; Walcott, Simone; Kuban, Vlastimil; Ferreira, Isabel C.F.R. (2017). Non-edible parts of Solanum stramoniifolium Jacq.-a new potent source of bioactive extracts rich in phenolic compounds for functional foods. Food and Function. ISSN 2042-6496. 8, p. 2013-2021en_EN
dc.identifier.doi10.1039/c7fo00297apt_PT
dc.identifier.issn2042-6496
dc.identifier.urihttp://hdl.handle.net/10198/15298
dc.language.isoeng
dc.peerreviewedyespt_PT
dc.titleNon-edible parts of Solanum stramoniifolium Jacq. - a new potent source of bioactive extracts rich in phenolic compounds for functional foodsen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F68344%2F2010/PT
oaire.fundingStream5876
oaire.fundingStreamSFRH
person.familyNameBarros
person.familyNameCalhelha
person.familyNameHeleno
person.familyNameAlves
person.familyNameFerreira
person.givenNameLillian
person.givenNameRicardo C.
person.givenNameSandrina A.
person.givenNameMaria José
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-id8B18-3095-6FC9
person.identifier.ciencia-idD618-B3A9-D312
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0001-7224-1098
person.identifier.orcid0000-0001-8506-4393
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridJ-2172-2014
person.identifier.ridL-5951-2014
person.identifier.ridM-6624-2016
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id30067731800
person.identifier.scopus-author-id16400584800
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticlept_PT
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