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Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds

2014Journal article Open access
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dc.contributor.authorPinho, Eva
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.contributor.authorCarvalho, Ana Maria
dc.contributor.authorSoares, Graça
dc.contributor.authorHenriques, Mariana
dc.date.accessioned2014-08-14T09:24:51Z
dc.date.available2014-08-14T09:24:51Z
dc.date.issued2014
dc.description.abstractThe present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds.por
dc.identifier.citationPinho, Eva; Ferreira, Isabel C.F.R.; Barros, Lillian; Carvalho, Ana Maria; Soares, Graça; Henriques, Mariana (2014). Antibacterial potential of North-eastern Portugal wild plant extracts and respective phenolic compounds. BioMed Research International. ISSN 2314-6141. p. 1-7por
dc.identifier.doi10.1155/2014/814590
dc.identifier.issn2314-6141
dc.identifier.urihttp://hdl.handle.net/10198/10154
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherHindawipor
dc.relationSFRH/BPD/4609/2000
dc.relationDEVELOPMENT OF A NEW ANTIMICROBIAL FABRIC FOR WOUND DRESSINGS
dc.relationStrategic Project - UI 264 - 2011-2012
dc.relationStrategic Project - UI 690 - 2011-2012
dc.titleAntibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compoundspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleDEVELOPMENT OF A NEW ANTIMICROBIAL FABRIC FOR WOUND DRESSINGS
oaire.awardTitleStrategic Project - UI 264 - 2011-2012
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/FARH/SFRH%2FBD%2F62665%2F2009/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/Incentivo%2FEQB%2FLA0023%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6820 - DCRRNI ID/PEst-C%2FCTM%2FUI0264%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.citation.titleBioMed Research Internationalpor
oaire.fundingStreamFARH
oaire.fundingStream3599-PPCDT
oaire.fundingStream6820 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameFerreira
person.familyNameBarros
person.familyNameCarvalho
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.givenNameAna Maria
person.identifier144781
person.identifier469085
person.identifierID G-7399-2011
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person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idD31A-35AF-E2A9
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0001-5508-5935
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id20336503900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
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